Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 541570..542154 Replicon chromosome
Accession NC_017059
Organism Rhodospirillum photometricum DSM 122

Toxin (Protein)


Gene name higB Uniprot ID H6SNX8
Locus tag RSPPHO_RS02370 Protein ID WP_014413690.1
Coordinates 541570..541851 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag RSPPHO_RS02375 Protein ID WP_014413691.1
Coordinates 541864..542154 (+) Length 97 a.a.

Genomic Context

RSPPHO_RS02370RSPPHO_RS02375RSPPHO_RS02380RSPPHO_RS19625RSPPHO_RS02400RSPPHO_RS20345RSPPHO_RS17415RSPPHO_RS02350RSPPHO_RS02355RSPPHO_RS02360RSPPHO_RS02365RSPPHO_RS02390RSPPHO_RS02395RSPPHO_RS18625RSPPHO_RS02410
Location: 541570..541851 (282 bp)
Type: Toxin
Protein ID: WP_014413690.1
Location: 541864..542154 (291 bp)
Type: Antitoxin
Protein ID: WP_014413691.1
Location: 542284..542727 (444 bp)
Type: Others
Protein ID: WP_014413692.1
Location: 542743..543219 (477 bp)
Type: Others
Protein ID: WP_157879053.1
Location: 543935..544456 (522 bp)
Type: Others
Protein ID: WP_041793824.1
Location: 545437..545784 (348 bp)
Type: Others
Protein ID: WP_162138079.1
Location: 536696..537778 (1083 bp)
Type: Others
Protein ID: WP_051013579.1
Location: 537784..538020 (237 bp)
Type: Others
Protein ID: WP_014413687.1
Location: 538033..538263 (231 bp)
Type: Others
Protein ID: WP_014413688.1
Location: 538260..540887 (2628 bp)
Type: Others
Protein ID: WP_041796365.1
Location: 540896..541141 (246 bp)
Type: Others
Protein ID: WP_041793810.1
Location: 543241..543495 (255 bp)
Type: Others
Protein ID: WP_041793816.1
Location: 543492..543791 (300 bp)
Type: Others
Protein ID: WP_041793819.1
Location: 544902..545351 (450 bp)
Type: Others
Protein ID: WP_162138078.1
Location: 545892..546320 (429 bp)
Type: Others
Protein ID: WP_041793833.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RSPPHO_RS17415536696..537778-1083WP_051013579.1tyrosine-type recombinase/integrase-
RSPPHO_RS02350537784..538020-237WP_014413687.1DNA-binding protein-
RSPPHO_RS02355538033..538263-231WP_014413688.1hypothetical protein-
RSPPHO_RS02360538260..540887-2628WP_041796365.1toprim domain-containing protein-
RSPPHO_RS02365540896..541141-246WP_041793810.1hypothetical protein-
RSPPHO_RS02370541570..541851+282WP_014413690.1type II toxin-antitoxin system RelE/ParE family toxinToxin
RSPPHO_RS02375541864..542154+291WP_014413691.1HigA family addiction module antidote proteinAntitoxin
RSPPHO_RS02380542284..542727+444WP_014413692.1hypothetical protein-
RSPPHO_RS19625542743..543219+477WP_157879053.1hypothetical protein-
RSPPHO_RS02390543241..543495-255WP_041793816.1ogr/Delta-like zinc finger family protein-
RSPPHO_RS02395543492..543791-300WP_041793819.1helix-turn-helix domain-containing protein-
RSPPHO_RS02400543935..544456+522WP_041793824.1helix-turn-helix domain-containing protein-
RSPPHO_RS18625544902..545351-450WP_162138078.1hypothetical protein-
RSPPHO_RS20345545437..545784+348WP_162138079.1hypothetical protein-
RSPPHO_RS02410545892..546320-429WP_041793833.1phage tail protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--512295..57378761492


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10548.17 Da        Isoelectric Point: 10.5531

>T26230 WP_014413690.1 NC_017059:541570-541851 [Pararhodospirillum photometricum DSM 122]
MIRSFKGKLARAVWEGQATKGFPADLLHPAQRKLIMLAAAIDLNTLRQPPGNRLEALKGNRKGQHSIRINDQWRICFRWG
DGAAEDVEIVDYH

Download         Length: 282 bp

>T26230 NC_017059:541570-541851 [Pararhodospirillum photometricum DSM 122]
ATGATCCGCAGCTTCAAAGGCAAACTGGCTCGGGCGGTGTGGGAAGGCCAGGCCACCAAGGGCTTTCCGGCGGACCTGCT
TCACCCGGCTCAACGCAAACTGATCATGCTTGCGGCGGCCATTGATCTCAACACCTTGCGCCAACCGCCGGGCAATCGCC
TGGAAGCCCTGAAGGGGAACCGGAAGGGACAGCACAGTATTCGCATCAACGATCAGTGGCGCATTTGCTTTCGTTGGGGC
GATGGCGCCGCCGAAGACGTTGAAATCGTCGATTATCACTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10359.03 Da        Isoelectric Point: 5.0892

>AT26230 WP_014413691.1 NC_017059:541864-542154 [Pararhodospirillum photometricum DSM 122]
MAGPVIHPGEVLREEFLVPLGLSAGAAAKACHVPRTRIERLVAEKTPITADTALRLGRLLGTGPEFWMNMQVLYDLAVAE
RATPDLDDITPVERAA

Download         Length: 291 bp

>AT26230 NC_017059:541864-542154 [Pararhodospirillum photometricum DSM 122]
ATGGCCGGTCCCGTTATCCACCCCGGGGAAGTGCTGCGCGAGGAATTCCTGGTCCCCCTGGGCCTGAGTGCTGGCGCTGC
GGCGAAGGCGTGCCATGTGCCACGCACCCGCATTGAGCGGTTGGTCGCGGAAAAGACCCCGATCACGGCCGACACCGCGT
TGCGCCTGGGCCGCCTGCTGGGCACCGGGCCGGAATTCTGGATGAACATGCAGGTGCTTTACGATCTGGCCGTTGCCGAG
CGGGCAACGCCAGACCTTGACGACATCACCCCCGTGGAGCGGGCGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH6SNX8

Antitoxin

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Source
ID
Structure
No matching records found

References