Detailed information of TA system TA261938

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2680488..2680814
• Replicon: chromosome
• Accession: NZ_CP109611
• Organism: Enterococcus faecalis strain AFL-109F

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OGM83_RS13030
• Protein ID: WP_116593266.1
• Coordinates: 2680674..2680814 (+)
• Length: 47 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2680488..2680672 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OGM83_RS13010 (2676160)	2676160..2676759	-	600	WP_225560887.1	RloB family protein	-
OGM83_RS13015 (2676768)	2676768..2678063	-	1296	WP_192177102.1	ATP-binding protein	-
OGM83_RS13020 (2678525)	2678525..2680141	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
OGM83_RS13025 (2680373)	2680373..2680555	+	183	WP_271232318.1	type I toxin-antitoxin system toxin PepG1	-
- (2680488)	2680488..2680672	-	185	NuclAT_9	-	Antitoxin
- (2680529)	2680529..2680672	-	144	NuclAT_12	-	-
OGM83_RS13030 (2680674)	2680674..2680814	+	141	WP_116593266.1	putative holin-like toxin	Toxin
- (2680747)	2680747..2681006	-	260	NuclAT_8	-	-
- (2680958)	2680958..2681007	+	50	NuclAT_14	-	-
- (2680788)	2680788..2681008	-	221	NuclAT_11	-	-
OGM83_RS13035 (2681009)	2681009..2684008	-	3000	WP_283658617.1	WxL domain-containing protein	-
OGM83_RS13040 (2683989)	2683989..2684357	-	369	WP_096398072.1	LPXTG cell wall anchor domain-containing protein	-
OGM83_RS13045 (2684743)	2684743..2685690	-	948	WP_002367506.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-46)

Sequences

Toxin

Protein

• Length: 47 a.a.
• Molecular weight: 5204.26 Da
• Isoelectric Point: 10.1092

>T261938 WP_116593266.1 NZ_CP109611:2680674-2680814 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 141 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT261938 NZ_CP109611:c2680672-2680488 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAATCAATGGTAAACATACCAA

Structures

Antitoxin