Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 482757..482989 Replicon chromosome
Accession NZ_CP109611
Organism Enterococcus faecalis strain AFL-109F

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag OGM83_RS02405 Protein ID WP_002355568.1
Coordinates 482757..482873 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 482784..482989 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGM83_RS02395 (478195) 478195..480453 + 2259 WP_002363179.1 DNA helicase PcrA -
OGM83_RS02400 (480579) 480579..482609 + 2031 WP_010828568.1 NAD-dependent DNA ligase LigA -
OGM83_RS02405 (482757) 482757..482873 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (482784) 482784..482989 - 206 NuclAT_3 - Antitoxin
OGM83_RS02410 (483191) 483191..483496 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
OGM83_RS02415 (483496) 483496..484965 + 1470 WP_002368026.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OGM83_RS02420 (484965) 484965..486395 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OGM83_RS02425 (486414) 486414..487502 + 1089 WP_002383001.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T261923 WP_002355568.1 NZ_CP109611:482757-482873 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT261923 NZ_CP109611:c482989-482784 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATGC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References