Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4277552..4278251 Replicon chromosome
Accession NZ_CP109606
Organism Pseudomonas putida strain QH1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A550F6I7
Locus tag OGV21_RS19375 Protein ID WP_019750831.1
Coordinates 4277955..4278251 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7D5VVT2
Locus tag OGV21_RS19370 Protein ID WP_029380550.1
Coordinates 4277552..4277953 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV21_RS19350 4272673..4273494 - 822 WP_003254229.1 transporter substrate-binding domain-containing protein -
OGV21_RS19355 4273570..4274511 - 942 WP_047604111.1 FAD-binding protein -
OGV21_RS19360 4274513..4275262 - 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
OGV21_RS19365 4275798..4277480 + 1683 WP_023389616.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
OGV21_RS19370 4277552..4277953 - 402 WP_029380550.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OGV21_RS19375 4277955..4278251 - 297 WP_019750831.1 type II toxin-antitoxin system MqsR family toxin Toxin
OGV21_RS19380 4278346..4279671 - 1326 WP_004573659.1 MFS transporter -
OGV21_RS19385 4279744..4280223 - 480 WP_264316358.1 histidine kinase -
OGV21_RS19390 4280392..4280868 - 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
OGV21_RS19395 4280990..4282615 - 1626 WP_264316359.1 twin-arginine translocation signal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11094.88 Da        Isoelectric Point: 9.8759

>T261902 WP_019750831.1 NZ_CP109606:c4278251-4277955 [Pseudomonas putida]
MEKRTPHCPLHRLQVLLSQGKVRTTQAATLGARSLGLGPYDMLDVVRGLSPGDFHKSMTSYNDHRIWQDVYRAQTAVGRV
YLKLTVVDDLLILSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14692.91 Da        Isoelectric Point: 4.9749

>AT261902 WP_029380550.1 NZ_CP109606:c4277953-4277552 [Pseudomonas putida]
MKCPLCGGAELVAQSRDMPYRYKGEATVIPDIFGDYCPTCGEAVLGMDEAQRMSDLMTAFERKVNAAVVDPGFIAAMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A550F6I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7D5VVT2

References