Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 310746..311350 Replicon chromosome
Accession NZ_CP109603
Organism Pseudomonas putida strain SEH01

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OGV19_RS01450 Protein ID WP_264311801.1
Coordinates 311030..311350 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OGV19_RS01445 Protein ID WP_264311800.1
Coordinates 310746..311033 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV19_RS01435 306759..309140 + 2382 WP_264311798.1 TonB-dependent receptor -
OGV19_RS01440 309148..310731 + 1584 WP_264311799.1 alpha/beta hydrolase-fold protein -
OGV19_RS01445 310746..311033 - 288 WP_264311800.1 NadS family protein Antitoxin
OGV19_RS01450 311030..311350 - 321 WP_264311801.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OGV19_RS01455 311504..313201 - 1698 WP_264311802.1 SulP family inorganic anion transporter -
OGV19_RS01465 313613..314497 - 885 WP_264311803.1 alpha/beta hydrolase -
OGV19_RS01470 314948..315640 - 693 WP_264311804.1 16S rRNA pseudouridine(516) synthase -
OGV19_RS01475 315674..315895 - 222 WP_264311805.1 cysteine-rich CWC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-87)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12257.22 Da        Isoelectric Point: 10.0949

>T261876 WP_264311801.1 NZ_CP109603:c311350-311030 [Pseudomonas putida]
MLFTETPLFTKRVKDLLEDDEYRLLQIRLMAQPDTGDLIEGTGGLRKVRIAANGHGKRGGARVIYYHFISKSQIAMLYIY
PKNEQPDLSAEQRKALKKIIENWRHA

Download         Length: 321 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10942.56 Da        Isoelectric Point: 8.7077

>AT261876 WP_264311800.1 NZ_CP109603:c311033-310746 [Pseudomonas putida]
MSRFFEELMESVQQMDDIVQGRQVPSRVFEVDALQVRSIRKSTGLSQVRFAEMIDVQVATLRNWEQGRREPTGPAKALLR
AIRNDPEHVLKALAY

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References