261752

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 253137..253788 Replicon plasmid pJL.02bL
Accession NZ_CP107574
Organism Pantoea dispersa strain JL.02bL

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OF384_RS20685 Protein ID WP_264251987.1
Coordinates 253137..253481 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8E1S3S0
Locus tag OF384_RS20690 Protein ID WP_058758775.1
Coordinates 253474..253788 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF384_RS20680 (OF384_20680) 249357..253034 + 3678 WP_264251986.1 autotransporter outer membrane beta-barrel domain-containing protein -
OF384_RS20685 (OF384_20685) 253137..253481 + 345 WP_264251987.1 toxin Toxin
OF384_RS20690 (OF384_20690) 253474..253788 + 315 WP_058758775.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OF384_RS20695 (OF384_20695) 253917..254342 + 426 WP_058781446.1 DCC1-like thiol-disulfide oxidoreductase family protein -
OF384_RS20700 (OF384_20700) 254339..254767 - 429 WP_058781447.1 arsenate reductase (glutaredoxin) -
OF384_RS20705 (OF384_20705) 254785..256068 - 1284 WP_264251988.1 arsenic transporter -
OF384_RS20710 (OF384_20710) 256138..256491 - 354 WP_264251989.1 metalloregulator ArsR/SmtB family transcription factor -
OF384_RS20715 (OF384_20715) 256840..258135 + 1296 WP_021509465.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..696693 696693


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-88)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13449.24 Da        Isoelectric Point: 9.6738

>T261752 WP_264251987.1 NZ_CP107574:253137-253481 [Pantoea dispersa]
MQATFIELSSFQKYRADYLSDDQFRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRNKGARGGIRIIYYWTNEKGQFIL
FSIYDKDQRDDLTKQQRDALAEALNVIKKGLRHD

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11984.71 Da        Isoelectric Point: 8.5238

>AT261752 WP_058758775.1 NZ_CP107574:253474-253788 [Pantoea dispersa]
MTERDIFSELMAGMQELKDHQDGKITLKTYKVSKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRAKP
NAQAVLLIRMVQQNPETLQTLAQF

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References