Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3224931..3225655 Replicon chromosome
Accession NZ_CP107573
Organism Pantoea dispersa strain JL.02bL

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OF384_RS15285 Protein ID WP_215480918.1
Coordinates 3224931..3225242 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OF384_RS15290 Protein ID WP_021313564.1
Coordinates 3225239..3225655 (+) Length 139 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF384_RS15270 (OF384_15270) 3220256..3222706 + 2451 WP_058776018.1 acyl-CoA dehydrogenase FadE -
OF384_RS15275 (OF384_15275) 3222891..3224051 + 1161 WP_264249307.1 pyridoxal phosphate-dependent aminotransferase -
OF384_RS15280 (OF384_15280) 3224039..3224809 + 771 WP_104189157.1 amidohydrolase -
OF384_RS15285 (OF384_15285) 3224931..3225242 + 312 WP_215480918.1 type II toxin-antitoxin system HigB family toxin Toxin
OF384_RS15290 (OF384_15290) 3225239..3225655 + 417 WP_021313564.1 transcriptional regulator Antitoxin
OF384_RS15295 (OF384_15295) 3225697..3227895 - 2199 WP_031279672.1 catalase/peroxidase HPI -
OF384_RS15300 (OF384_15300) 3228190..3228525 - 336 WP_021507290.1 hydroxyisourate hydrolase -
OF384_RS15305 (OF384_15305) 3228522..3229016 - 495 WP_058769329.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
OF384_RS15310 (OF384_15310) 3229029..3230288 - 1260 WP_132466329.1 allantoate amidohydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 104 a.a.        Molecular weight: 12183.06 Da        Isoelectric Point: 10.3546

>T261748 WP_215480918.1 NZ_CP107573:3224931-3225242 [Pantoea dispersa]
MHIISRKVFNEATQRFPNDAAALDATYRLLSGHDFADPQALKAWFPSLDRMKYRAKWWVINVGGNNLRLMFFADFVAKRV
FVKHIVTHAEYDKLVKHYRENKE

Download         Length: 312 bp


Antitoxin


Download         Length: 139 a.a.        Molecular weight: 15331.57 Da        Isoelectric Point: 7.4011

>AT261748 WP_021313564.1 NZ_CP107573:3225239-3225655 [Pantoea dispersa]
MISEAIQASNNLIKAVPLLGGSQSRADYEQALELVEYLVEHQPGHPLIEMLAVKVAKYEETAAEFAAFNARTQALPGGVA
LLRVLMDQHGLNQSSFVAEIGQRSYVNRILKGERRLTDKHKAALARRFNLPFEAFREA

Download         Length: 417 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References