Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1507776..1508370 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag OEG81_RS07255 Protein ID WP_264132053.1
Coordinates 1508092..1508370 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OEG81_RS07250 Protein ID WP_264132052.1
Coordinates 1507776..1508078 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS07230 (OEG81_07230) 1503006..1505348 - 2343 WP_264132047.1 ATP-dependent DNA helicase -
OEG81_RS07235 (OEG81_07235) 1505345..1507045 - 1701 WP_264132048.1 VRR-NUC domain-containing protein -
OEG81_RS07240 (OEG81_07240) 1507269..1507469 + 201 WP_264132050.1 CsbD family protein -
OEG81_RS07245 (OEG81_07245) 1507529..1507693 + 165 WP_264132051.1 DUF1328 domain-containing protein -
OEG81_RS07250 (OEG81_07250) 1507776..1508078 - 303 WP_264132052.1 HigA family addiction module antitoxin Antitoxin
OEG81_RS07255 (OEG81_07255) 1508092..1508370 - 279 WP_264132053.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG81_RS07260 (OEG81_07260) 1508542..1509030 + 489 WP_264132054.1 flagellar protein FlhE -
OEG81_RS07265 (OEG81_07265) 1509183..1509890 - 708 WP_264132518.1 haloacid dehalogenase type II -
OEG81_RS07270 (OEG81_07270) 1509958..1511400 - 1443 WP_264132055.1 sodium:solute symporter family protein -
OEG81_RS07275 (OEG81_07275) 1511887..1512669 + 783 WP_264132056.1 3-oxoacyl-ACP reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(19-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-84)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10566.21 Da        Isoelectric Point: 9.3251

>T261726 WP_264132053.1 NZ_CP107548:c1508370-1508092 [Pusillimonas sp. M17]
MIKSFRCADTQALFEGRHVARLANIKSIAERKLQMLDSANTLIFLRSPPGNRLEALKGNRIGQHSIRINDQWRICFVWTM
EGPDGVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11062.85 Da        Isoelectric Point: 9.7330

>AT261726 WP_264132052.1 NZ_CP107548:c1508078-1507776 [Pusillimonas sp. M17]
MSKNGMRPVHPGEILREEYLAPLGMSVNALSAMLHVPATRMNEIVRERRGITPDTALRLAALFGGDASSWLNLQQTYDLK
NTEAKVAKLIAKQIQPLEHA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References