Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2441024..2441208 Replicon chromosome
Accession NC_016941
Organism Staphylococcus aureus subsp. aureus MSHR1132

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag SAMSHR1132_RS11990 Protein ID WP_000482653.1
Coordinates 2441101..2441208 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2441024..2441084 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMSHR1132_RS11975 2436816..2438549 - 1734 WP_000486509.1 ABC transporter ATP-binding protein/permease -
SAMSHR1132_RS11980 2438574..2440337 - 1764 WP_001064639.1 ABC transporter ATP-binding protein/permease -
- 2441024..2441084 + 61 - - Antitoxin
SAMSHR1132_RS11990 2441101..2441208 - 108 WP_000482653.1 type I toxin-antitoxin system Fst family toxin Toxin
SAMSHR1132_RS11995 2441343..2441729 - 387 WP_000779346.1 flippase GtxA -
SAMSHR1132_RS12000 2441997..2443139 + 1143 WP_001177027.1 glycerate kinase -
SAMSHR1132_RS12005 2443198..2443857 + 660 WP_000831306.1 membrane protein -
SAMSHR1132_RS12010 2444042..2445253 + 1212 WP_001191960.1 multidrug effflux MFS transporter -
SAMSHR1132_RS12015 2445369..2445848 - 480 WP_000875877.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4025.81 Da        Isoelectric Point: 11.0582

>T26128 WP_000482653.1 NC_016941:c2441208-2441101 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26128 NC_016941:c2441208-2441101 [Staphylococcus argenteus]
ATGTTCAATTTATTGATTAACATCATGACTACAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26128 NC_016941:2441024-2441084 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References