Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1827297..1827477 Replicon chromosome
Accession NC_016941
Organism Staphylococcus aureus subsp. aureus MSHR1132

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAMSHR1132_RS14115 Protein ID WP_001801861.1
Coordinates 1827297..1827392 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1827420..1827477 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMSHR1132_RS08590 1822476..1823102 + 627 WP_000669020.1 hypothetical protein -
SAMSHR1132_RS08595 1823143..1823484 + 342 WP_000627553.1 DUF3969 family protein -
SAMSHR1132_RS08600 1823585..1824157 + 573 WP_000414227.1 hypothetical protein -
SAMSHR1132_RS08605 1824355..1824912 - 558 WP_000864134.1 ImmA/IrrE family metallo-endopeptidase -
SAMSHR1132_RS08610 1825096..1825281 - 186 WP_000809859.1 hypothetical protein -
SAMSHR1132_RS08615 1825283..1825459 - 177 WP_000375476.1 hypothetical protein -
SAMSHR1132_RS08620 1825470..1825853 - 384 WP_000070811.1 hypothetical protein -
SAMSHR1132_RS14115 1827297..1827392 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1827420..1827477 - 58 - - Antitoxin
SAMSHR1132_RS08630 1827515..1827616 + 102 WP_042355399.1 hypothetical protein -
SAMSHR1132_RS08635 1827751..1828203 - 453 WP_000428250.1 DUF1433 domain-containing protein -
SAMSHR1132_RS08640 1828241..1829851 + 1611 WP_001026719.1 hypothetical protein -
SAMSHR1132_RS08645 1829866..1830165 + 300 WP_000095394.1 WXG100 family type VII secretion target -
SAMSHR1132_RS08650 1830292..1831557 - 1266 WP_000072359.1 restriction endonuclease subunit S -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T26120 WP_001801861.1 NC_016941:1827297-1827392 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T26120 NC_016941:1827297-1827392 [Staphylococcus argenteus]
GTGATGCTTATTTTCGTTCACATCATAGCGCCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT26120 NC_016941:c1827477-1827420 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References