Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 982077..982326 Replicon chromosome
Accession NC_016941
Organism Staphylococcus aureus subsp. aureus MSHR1132

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag SAMSHR1132_RS04600 Protein ID WP_014373809.1
Coordinates 982077..982184 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 982179..982326 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMSHR1132_RS04575 978756..979325 - 570 WP_000287261.1 competence protein ComK -
SAMSHR1132_RS04580 979535..979753 + 219 WP_000876831.1 IDEAL domain-containing protein -
SAMSHR1132_RS04585 979834..980820 - 987 WP_000668810.1 lipoate--protein ligase -
SAMSHR1132_RS04590 981015..981191 + 177 WP_000214898.1 YkvS family protein -
SAMSHR1132_RS04595 981206..981808 + 603 WP_001033872.1 CPBP family intramembrane metalloprotease -
SAMSHR1132_RS04600 982077..982184 + 108 WP_014373809.1 putative holin-like toxin Toxin
- 982179..982326 - 148 - - Antitoxin
SAMSHR1132_RS04605 982822..983106 + 285 WP_000790904.1 lactococcin 972 family bacteriocin -
SAMSHR1132_RS04610 983150..985114 + 1965 WP_000870810.1 bacteriocin-associated integral membrane family protein -
SAMSHR1132_RS04615 985117..985437 + 321 WP_000668624.1 YxeA family protein -
SAMSHR1132_RS04620 985434..986075 + 642 WP_000571193.1 ABC transporter ATP-binding protein -
SAMSHR1132_RS04625 986163..986423 - 261 WP_169929182.1 hypothetical protein -
SAMSHR1132_RS04630 986746..987033 + 288 WP_000410715.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3815.72 Da        Isoelectric Point: 10.8004

>T26119 WP_014373809.1 NC_016941:982077-982184 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIINLNNKK

Download         Length: 108 bp

>T26119 NC_016941:982077-982184 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin


Download         Length: 148 bp

>AT26119 NC_016941:c982326-982179 [Staphylococcus argenteus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAA
AGACGGTGACTAAATGAGTTTTTCTTTAACCATCATTCTTTGTCAAAGTTTTGAAATGATGGTTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References