Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2175788..2176051 Replicon chromosome
Accession NC_016928
Organism Staphylococcus aureus subsp. aureus M013

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag M013TW_RS10900 Protein ID WP_001802298.1
Coordinates 2175947..2176051 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2175788..2175952 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M013TW_RS10880 2172025..2172690 - 666 WP_001024088.1 SDR family oxidoreductase -
M013TW_RS10885 2172842..2173162 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
M013TW_RS10890 2173164..2174141 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
M013TW_RS10895 2174407..2175498 + 1092 WP_000495695.1 hypothetical protein -
- 2175788..2175952 + 165 - - Antitoxin
M013TW_RS10900 2175947..2176051 - 105 WP_001802298.1 hypothetical protein Toxin
M013TW_RS10905 2176212..2176695 - 484 Protein_2060 recombinase family protein -
M013TW_RS10910 2176738..2177874 - 1137 Protein_2061 SAP domain-containing protein -
M013TW_RS10915 2178163..2178255 + 93 WP_031844941.1 hypothetical protein -
M013TW_RS10920 2178950..2179807 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
M013TW_RS10925 2179875..2180657 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26113 WP_001802298.1 NC_016928:c2176051-2175947 [Staphylococcus aureus subsp. aureus M013]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26113 NC_016928:c2176051-2175947 [Staphylococcus aureus subsp. aureus M013]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT26113 NC_016928:2175788-2175952 [Staphylococcus aureus subsp. aureus M013]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References