Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 3142385..3142972 Replicon chromosome
Accession NZ_CP107241
Organism Xanthomonas hortorum strain Oregano 108

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OEG85_RS13470 Protein ID WP_268211660.1
Coordinates 3142694..3142972 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OEG85_RS13465 Protein ID WP_268211659.1
Coordinates 3142385..3142684 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG85_RS13440 (OEG85_13435) 3137889..3138773 + 885 WP_006451802.1 MinD/ParA family protein -
OEG85_RS13445 (OEG85_13440) 3138770..3139543 + 774 WP_023903918.1 RNA polymerase sigma factor FliA -
OEG85_RS13450 (OEG85_13445) 3139579..3139971 + 393 WP_002813536.1 chemotaxis response regulator CheY -
OEG85_RS13455 (OEG85_13450) 3139971..3140597 + 627 WP_006450905.1 protein phosphatase CheZ -
OEG85_RS13460 (OEG85_13455) 3140600..3142258 + 1659 WP_268211658.1 chemotaxis protein CheA -
OEG85_RS13465 (OEG85_13460) 3142385..3142684 - 300 WP_268211659.1 HigA family addiction module antitoxin Antitoxin
OEG85_RS13470 (OEG85_13465) 3142694..3142972 - 279 WP_268211660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG85_RS13475 (OEG85_13470) 3143599..3144339 + 741 WP_006452732.1 flagellar motor protein -
OEG85_RS13480 (OEG85_13475) 3144347..3145321 + 975 WP_268211661.1 flagellar motor protein MotD -
OEG85_RS13485 (OEG85_13480) 3145323..3146105 + 783 WP_006452730.1 ParA family protein -
OEG85_RS13490 (OEG85_13485) 3146102..3147352 + 1251 WP_268211662.1 chemotaxis protein CheW -
OEG85_RS13495 (OEG85_13490) 3147456..3147764 + 309 WP_006448510.1 STAS domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-67)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10593.05 Da        Isoelectric Point: 8.5635

>T260549 WP_268211660.1 NZ_CP107241:c3142972-3142694 [Xanthomonas hortorum]
MIQSFRCKHTRALFEGASPRQFRSMQAAAERKLQLLDSAQTLEFLRSPPGNRLELLAGTRAGQHSIRINDQWRVCFVWTD
AGPEHVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10801.40 Da        Isoelectric Point: 10.1958

>AT260549 WP_268211659.1 NZ_CP107241:c3142684-3142385 [Xanthomonas hortorum]
MRPNNKLRAIHPGEILREDFMLPLGLTINGLARALDVPATRIHSIVHGERAISADTAARLARHFGGDAASWLALQATYDL
KTLPNTGEIERNVQPRVAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References