Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 47001..47708 Replicon chromosome
Accession NZ_CP107077
Organism Kosakonia cowanii strain LT-1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag ODS25_RS00230 Protein ID WP_124966952.1
Coordinates 47403..47708 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag ODS25_RS00225 Protein ID WP_042715055.1
Coordinates 47001..47402 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODS25_RS00205 42778..43725 + 948 WP_200135116.1 ABC transporter permease -
ODS25_RS00210 43722..44705 + 984 WP_263753641.1 ABC transporter ATP-binding protein -
ODS25_RS00215 44702..45676 + 975 WP_054802734.1 ATP-binding cassette domain-containing protein -
ODS25_RS00220 45750..46943 + 1194 WP_042715056.1 zinc-dependent alcohol dehydrogenase -
ODS25_RS00225 47001..47402 - 402 WP_042715055.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
ODS25_RS00230 47403..47708 - 306 WP_124966952.1 type II toxin-antitoxin system MqsR family toxin Toxin
ODS25_RS00235 47865..48518 - 654 WP_263753643.1 oxygen-insensitive NAD(P)H nitroreductase -
ODS25_RS00240 48713..49648 + 936 WP_263754789.1 LysR family transcriptional regulator -
ODS25_RS00245 49710..50663 + 954 WP_263753644.1 aldo/keto reductase -
ODS25_RS00250 50770..51942 - 1173 WP_263753645.1 multidrug effflux MFS transporter -
ODS25_RS00255 52050..52652 - 603 WP_263753646.1 XRE family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-100)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11560.57 Da        Isoelectric Point: 8.9492

>T260506 WP_124966952.1 NZ_CP107077:c47708-47403 [Kosakonia cowanii]
MEKGTPHVRLHIVKRMVLEGKVRTTASAVAGAIELGFNPPPFDEMCAVILALTSEDFFKSMTAYADHTVWHDVYRPVWKR
QKLYLKLIVSDDVLIVSFKER

Download         Length: 306 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14947.15 Da        Isoelectric Point: 8.4858

>AT260506 WP_042715055.1 NZ_CP107077:c47402-47001 [Kosakonia cowanii]
MKCPVCGAAGLKHDTRNIEYRYKGKVTTLTAIAGEYCDACGEIIFDRLNGEHYSKQVAAFVRKVNAEEVDPQFIATIRKR
FNLDQRQAAEMFGGGANAFSRYETGRVAPPRPLVLLFKALDKHPELFEELKHA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References