Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 231312..231897 Replicon chromosome
Accession NZ_CP106869
Organism Xanthomonas sp. AM6

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag OCJ37_RS00955 Protein ID WP_263111795.1
Coordinates 231312..231593 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OCJ37_RS00960 Protein ID WP_263111796.1
Coordinates 231607..231897 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCJ37_RS00945 (OCJ37_00945) 227508..228650 - 1143 WP_263111793.1 ribonuclease H-like domain-containing protein -
OCJ37_RS00950 (OCJ37_00950) 228647..231142 - 2496 WP_263111794.1 DEAD/DEAH box helicase -
OCJ37_RS00955 (OCJ37_00955) 231312..231593 + 282 WP_263111795.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCJ37_RS00960 (OCJ37_00960) 231607..231897 + 291 WP_263111796.1 HigA family addiction module antitoxin Antitoxin
OCJ37_RS00965 (OCJ37_00965) 232047..232709 + 663 WP_263111797.1 hemolysin III family protein -
OCJ37_RS00970 (OCJ37_00970) 232833..233312 + 480 WP_263111798.1 hypothetical protein -
OCJ37_RS00975 (OCJ37_00975) 233648..234487 - 840 WP_263111799.1 helix-turn-helix transcriptional regulator -
OCJ37_RS00980 (OCJ37_00980) 234591..235484 + 894 WP_263111800.1 SDR family oxidoreductase -
OCJ37_RS00985 (OCJ37_00985) 235996..236547 - 552 WP_263111801.1 DUF1311 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(21-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10774.28 Da        Isoelectric Point: 10.7841

>T259911 WP_263111795.1 NZ_CP106869:231312-231593 [Xanthomonas sp. AM6]
VIRTFVDKEAEKIWQGTPSRRLPADIQVVARRKPRMLNSAAALDDLRVPPANRLEALKGNRKGQYSIRINDQWRVRFQWK
DGDAPNVEIVDDH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10301.89 Da        Isoelectric Point: 10.0800

>AT259911 WP_263111796.1 NZ_CP106869:231607-231897 [Xanthomonas sp. AM6]
MKTLPNIHPGDVLLEEFLTPLGISQNALARAAGVPPRRINEIVLGKRSVTADSAIRLAAALGTSERFWLGLQADYDLEQA
RRALGAQAGKIERIAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References