Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2805525..2806039 Replicon chromosome
Accession NZ_CP106798
Organism Streptomyces sp. HUAS 15-9

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N8I87_RS12900 Protein ID WP_263208444.1
Coordinates 2805785..2806039 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N8I87_RS12895 Protein ID WP_142164117.1
Coordinates 2805525..2805788 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8I87_RS12870 (N8I87_12870) 2801433..2802167 + 735 WP_263208438.1 TetR/AcrR family transcriptional regulator -
N8I87_RS12875 (N8I87_12875) 2802300..2802731 + 432 WP_263208439.1 hypothetical protein -
N8I87_RS12885 (N8I87_12885) 2803554..2805241 - 1688 Protein_2558 hypothetical protein -
N8I87_RS12890 (N8I87_12890) 2805268..2805405 + 138 WP_263208441.1 hypothetical protein -
N8I87_RS12895 (N8I87_12895) 2805525..2805788 + 264 WP_142164117.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N8I87_RS12900 (N8I87_12900) 2805785..2806039 + 255 WP_263208444.1 Txe/YoeB family addiction module toxin Toxin
N8I87_RS12920 (N8I87_12920) 2806865..2807170 + 306 WP_263208446.1 YtxH domain-containing protein -
N8I87_RS12925 (N8I87_12925) 2807263..2808714 + 1452 WP_263208448.1 FGGY family carbohydrate kinase -
N8I87_RS12930 (N8I87_12930) 2808875..2810608 + 1734 WP_263208449.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10108.46 Da        Isoelectric Point: 8.4000

>T259833 WP_263208444.1 NZ_CP106798:2805785-2806039 [Streptomyces sp. HUAS 15-9]
VKISFTSHAWEDYTYWAENDRKMVKRINKLIDDTMRDPFKGIGKPEPLKGDLSGYWSRRIDDTHRLVYKPSDDELMIVQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9747.86 Da        Isoelectric Point: 5.1273

>AT259833 WP_142164117.1 NZ_CP106798:2805525-2805788 [Streptomyces sp. HUAS 15-9]
MSITASEARQNLFPLIEQVNEDHAPVHITSRKGNAVLMSEEDFSSWTETVHLLRSPKNARRLLDSIAEAEAGKAQHRELI
DPDAERA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References