Detailed information of TA system TA259739

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 419607..420087
• Replicon: chromosome
• Accession: NZ_CP106757
• Organism: Enterococcus faecalis strain NY13410

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N8I78_RS01980
• Protein ID: WP_021164441.1
• Coordinates: 419986..420087 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	419607..419811 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N8I78_RS01960	414963..415859	-	897	WP_002354953.1	YitT family protein	-
N8I78_RS01965	416420..416920	-	501	WP_002378961.1	cysteine hydrolase family protein	-
N8I78_RS01970	417091..419361	+	2271	WP_002399785.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
N8I78_RS01975	419552..419653	+	102	WP_021164442.1	putative holin-like toxin	-
-	419607..419811	-	205	-	-	Antitoxin
N8I78_RS01980	419986..420087	+	102	WP_021164441.1	putative holin-like toxin	Toxin
N8I78_RS01985	420269..420721	-	453	WP_002378959.1	YueI family protein	-
N8I78_RS01990	420906..421853	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
N8I78_RS01995	421850..422815	+	966	WP_002387376.1	iron chelate uptake ABC transporter family permease subunit	-
N8I78_RS02000	422812..423567	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
N8I78_RS02005	423606..424559	+	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T259739 WP_021164441.1 NZ_CP106757:419986-420087 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 205 bp

>AT259739 NZ_CP106757:c419811-419607 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA

Structures

Antitoxin