Detailed information of TA system TA259734

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 265701..266099
• Replicon: chromosome
• Accession: NZ_CP106757
• Organism: Enterococcus faecalis strain NY13410

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N8I78_RS01270
• Protein ID: WP_021164545.1
• Coordinates: 265701..265805 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	265945..266099 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N8I78_RS01260	261016..261159	-	144	WP_002387585.1	putative holin-like toxin	-
N8I78_RS01265	261753..265511	+	3759	WP_010706868.1	WxL domain-containing protein	-
N8I78_RS01270	265701..265805	-	105	WP_021164545.1	putative holin-like toxin	Toxin
-	265945..266099	+	155	-	-	Antitoxin
N8I78_RS01275	266407..268023	-	1617	WP_002379014.1	phosphatase PAP2/LCP family protein	-
N8I78_RS01280	268485..269780	+	1296	WP_002379013.1	ATP-binding protein	-
N8I78_RS01285	269789..270421	+	633	WP_002358972.1	RloB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T259734 WP_021164545.1 NZ_CP106757:c265805-265701 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 155 bp

>AT259734 NZ_CP106757:265945-266099 [Enterococcus faecalis]
TTTTTAGGTAAGTGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Structures

Antitoxin