Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 70992..71700 Replicon chromosome
Accession NZ_CP106754
Organism Kosakonia sp. ML.JS2a

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag N7922_RS00310 Protein ID WP_263098731.1
Coordinates 71395..71700 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag N7922_RS00305 Protein ID WP_263098730.1
Coordinates 70992..71393 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7922_RS00280 (N7922_00280) 66025..66906 + 882 WP_263098729.1 LysR family transcriptional regulator -
N7922_RS00285 (N7922_00285) 66953..67810 - 858 WP_061492440.1 fumarylacetoacetate hydrolase family protein -
N7922_RS00290 (N7922_00290) 67837..68448 - 612 WP_209446755.1 L(+)-tartrate dehydratase subunit beta -
N7922_RS00295 (N7922_00295) 68442..69341 - 900 WP_209446753.1 L(+)-tartrate dehydratase subunit alpha -
N7922_RS00300 (N7922_00300) 69362..70657 - 1296 WP_061492442.1 MFS transporter -
N7922_RS00305 (N7922_00305) 70992..71393 - 402 WP_263098730.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
N7922_RS00310 (N7922_00310) 71395..71700 - 306 WP_263098731.1 type II toxin-antitoxin system MqsR family toxin Toxin
N7922_RS00315 (N7922_00315) 71811..72464 - 654 WP_263098732.1 oxygen-insensitive NAD(P)H nitroreductase -
N7922_RS00320 (N7922_00320) 72652..73587 + 936 WP_263098733.1 LysR family transcriptional regulator -
N7922_RS00325 (N7922_00325) 74023..75123 + 1101 WP_263098734.1 alcohol dehydrogenase catalytic domain-containing protein -
N7922_RS00330 (N7922_00330) 75162..75827 + 666 WP_263098735.1 dihydrofolate reductase family protein -
N7922_RS00335 (N7922_00335) 75856..76458 + 603 WP_263098736.1 DUF1349 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11529.52 Da        Isoelectric Point: 8.0751

>T259694 WP_263098731.1 NZ_CP106754:c71700-71395 [Kosakonia sp. ML.JS2a]
MEKGTPHTRLHIVKQMVTDGKIKITSSAIAGAIELGFTVPPFDEMCTVILSLTMTDFFKSMTAYADHTIWHDVYRPLWNG
QRIYLKLIVSNDVLIVSFKER

Download         Length: 306 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15135.34 Da        Isoelectric Point: 8.4956

>AT259694 WP_263098730.1 NZ_CP106754:c71393-70992 [Kosakonia sp. ML.JS2a]
MKCPVCGGAELKHETRDVAYEYKNRKTLIKNVMGDFCDNCGEIVFDRINGEHYAKQVAAFVRNVNANEVDPHFIARVRKR
FNLDQRQAAEIFGGGANAFSRYETGRVAPPKPLILLFKALDKHPELFEELKHA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References