Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 897630..898281 Replicon chromosome
Accession NZ_CP106752
Organism Psychrobacter sp. SC65A.3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OEG80_RS03920 Protein ID WP_263241852.1
Coordinates 897934..898281 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A197ET80
Locus tag OEG80_RS03915 Protein ID WP_068408813.1
Coordinates 897630..897932 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG80_RS03890 (SC65A3_00791) 893058..894227 - 1170 WP_263241846.1 CynX/NimT family MFS transporter -
OEG80_RS03895 (SC65A3_00792) 894398..894868 - 471 WP_020443882.1 cyanase -
OEG80_RS03900 (SC65A3_00793) 894992..895651 - 660 WP_263241847.1 carbonic anhydrase -
OEG80_RS03905 (SC65A3_00794) 895844..896725 + 882 WP_263241848.1 transcriptional regulator CynR -
OEG80_RS03910 (SC65A3_00795) 897116..897409 + 294 WP_020443287.1 hypothetical protein -
OEG80_RS03915 (SC65A3_00796) 897630..897932 - 303 WP_068408813.1 XRE family transcriptional regulator Antitoxin
OEG80_RS03920 (SC65A3_00797) 897934..898281 - 348 WP_263241852.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG80_RS03925 (SC65A3_00798) 898548..898784 + 237 WP_263241854.1 hypothetical protein -
OEG80_RS03930 (SC65A3_00799) 898845..899477 - 633 WP_263241855.1 recombinase family protein -
OEG80_RS03935 (SC65A3_00802) 900011..901176 + 1166 WP_263241287.1 IS3 family transposase -
OEG80_RS03940 (SC65A3_00803) 901219..901443 - 225 WP_263241857.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 895844..911762 15918


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-81)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13383.37 Da        Isoelectric Point: 7.8524

>T259691 WP_263241852.1 NZ_CP106752:c898281-897934 [Psychrobacter sp. SC65A.3]
MWTVITTELFNQWFDQQDDSTQEKVLAALMVLEQQGPSLGRPLVDTVYDSKFTNMKELRVQHRGKPLRAFFAFDPKRQAI
VLCIGDKGNKKRFYKEMLATADQQYECHLRTLGDP

Download         Length: 348 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11352.21 Da        Isoelectric Point: 9.7249

>AT259691 WP_068408813.1 NZ_CP106752:c897932-897630 [Psychrobacter sp. SC65A.3]
MTKTLQEMLAERSLDSRARIKQLAEQLLLENQLSRIREELEISQKELAQTMGIKQPSLSAIENRGNDLKISTMKKYVEAM
GGKLRIDVELPTGKHIGFNV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A197ET80

References