Detailed information of TA system TA259616

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1567100..1567425
• Replicon: chromosome
• Accession: NZ_CP106671
• Organism: Bacillus subtilis strain SRCM116301

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N7980_RS08110
• Protein ID: WP_128751232.1
• Coordinates: 1567246..1567425 (-)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1567100..1567322 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N7980_RS08065 (1562469)	1562469..1562780	+	312	WP_003229923.1	YqbF domain-containing protein	-
N7980_RS08070 (1562784)	1562784..1563179	+	396	WP_004398566.1	DUF3199 family protein	-
N7980_RS08075 (1563176)	1563176..1563538	+	363	WP_003229925.1	YqbH/XkdH family protein	-
N7980_RS08080 (1563535)	1563535..1564038	+	504	WP_003246050.1	HK97 gp10 family phage protein	-
N7980_RS08085 (1564051)	1564051..1564488	+	438	WP_003229927.1	hypothetical protein	-
N7980_RS08090 (1564485)	1564485..1564676	+	192	WP_010886574.1	hypothetical protein	-
N7980_RS08095 (1564677)	1564677..1566077	+	1401	WP_003229929.1	phage tail sheath family protein	-
N7980_RS08100 (1566080)	1566080..1566523	+	444	WP_003229930.1	phage tail tube protein	-
N7980_RS08105 (1566777)	1566777..1566866	-	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
- (1567100)	1567100..1567322	+	223	NuclAT_0	-	Antitoxin
- (1567100)	1567100..1567322	+	223	NuclAT_0	-	Antitoxin
- (1567100)	1567100..1567322	+	223	NuclAT_0	-	Antitoxin
- (1567100)	1567100..1567322	+	223	NuclAT_0	-	Antitoxin
N7980_RS08110 (1567246)	1567246..1567425	-	180	WP_128751232.1	type I toxin-antitoxin system toxin TxpA	Toxin
N7980_RS08115 (1567571)	1567571..1568020	+	450	WP_032722171.1	phage portal protein	-
N7980_RS08120 (1568062)	1568062..1568199	+	138	WP_021480099.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1537969..1608125	70156

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6755.19 Da
• Isoelectric Point: 8.0288

>T259616 WP_128751232.1 NZ_CP106671:c1567425-1567246 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

Antitoxin

Nucleotide

• Length: 223 bp

>AT259616 NZ_CP106671:1567100-1567322 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Antitoxin