259492

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 764054..764748 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag RS71_RS03510 Protein ID WP_057082976.1
Coordinates 764054..764458 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID G7LPQ3
Locus tag RS71_RS03515 Protein ID WP_009111694.1
Coordinates 764455..764748 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS03490 759443..759664 - 222 WP_022634593.1 acyl carrier protein -
RS71_RS03495 759683..761116 - 1434 WP_022634594.1 AMP-binding protein -
RS71_RS03500 761113..762231 - 1119 WP_057082977.1 cytochrome c552 -
RS71_RS03505 762361..763500 - 1140 WP_022634597.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
RS71_RS03510 764054..764458 - 405 WP_057082976.1 type II toxin-antitoxin system YafO family toxin Toxin
RS71_RS03515 764455..764748 - 294 WP_009111694.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
RS71_RS03520 764973..766166 + 1194 WP_057083010.1 SIR2 family protein -
RS71_RS03525 766171..768036 + 1866 WP_072143108.1 ATP-binding protein -
RS71_RS03530 768045..768254 + 210 WP_072143107.1 KTSC domain-containing protein -
RS71_RS03535 768663..768779 - 117 WP_263083506.1 type 4 pilus major pilin -
RS71_RS03540 768970..769179 + 210 WP_263083309.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(29-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15500.84 Da        Isoelectric Point: 7.1284

>T259492 WP_057082976.1 NZ_CP104920:c764458-764054 [Dickeya solani]
MSIRIFKSALIRQQLSQQELDDLAADFLSYKKDGVLPDTFGRDAPYDDDRTYPLIKEEQVAHIHLADADAPFPKFLRQFK
RTSDQAHLVYCQGAMDPDAYLLIIILKPEAHKMARNNNHMHKIGMMAEAFRMKH

Download         Length: 405 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10993.46 Da        Isoelectric Point: 4.9167

>AT259492 WP_009111694.1 NZ_CP104920:c764748-764455 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVHTAARFRPTAERLSDIADSG
QKLLQNASDKDLTEFTE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1UKC7

References