Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 568800..569469 Replicon chromosome
Accession NZ_CP104917
Organism Avibacterium paragallinarum strain AP-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N8E87_RS02800 Protein ID WP_264245847.1
Coordinates 568800..569165 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N8E87_RS02805 Protein ID WP_017807009.1
Coordinates 569167..569469 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E87_RS02780 (N8E87_02780) 563919..564647 + 729 WP_264245841.1 30S ribosomal protein S2 -
N8E87_RS02785 (N8E87_02785) 564779..565624 + 846 WP_264245842.1 translation elongation factor Ts -
N8E87_RS02790 (N8E87_02790) 565919..567508 - 1590 WP_264245844.1 peptide chain release factor 3 -
N8E87_RS02795 (N8E87_02795) 567690..568550 + 861 WP_264245845.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
N8E87_RS02800 (N8E87_02800) 568800..569165 + 366 WP_264245847.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E87_RS02805 (N8E87_02805) 569167..569469 + 303 WP_017807009.1 XRE family transcriptional regulator Antitoxin
N8E87_RS02810 (N8E87_02810) 569581..570420 + 840 WP_264245849.1 SDR family oxidoreductase -
N8E87_RS02815 (N8E87_02815) 570511..571851 + 1341 WP_017807007.1 argininosuccinate synthase -
N8E87_RS02820 (N8E87_02820) 571968..572843 + 876 WP_264245851.1 VirK/YbjX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-81)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14097.38 Da        Isoelectric Point: 6.3716

>T259486 WP_264245847.1 NZ_CP104917:568800-569165 [Avibacterium paragallinarum]
MKQEWKVILQDPLLNWLETLAEDDLLKVYAALALLSTEGPQLGRPYADTIQGSKYTNLKELRVQSKLSVFRLFYIFDPIR
QAIVLCGGDKKGKKEKLFYKEMITLAEQTYDNYLSEFLKEQ

Download         Length: 366 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11238.21 Da        Isoelectric Point: 9.5655

>AT259486 WP_017807009.1 NZ_CP104917:569167-569469 [Avibacterium paragallinarum]
MSVAFKDLMNKLPAEKQAKVKAIADDMRMELQLYRIREELELSQKQMAEALNISQPSVVALEKRGNDIKLSSVKRYIEAM
GGVLNLSIELPTGKTVTFNL

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References