259467

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 54675..55333 Replicon plasmid punamed1
Accession NZ_CP104909
Organism Acinetobacter baumannii strain YZM-0314

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N7297_RS19040 Protein ID WP_000312250.1
Coordinates 54974..55333 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N7297_RS19035 Protein ID WP_001096429.1
Coordinates 54675..54974 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7297_RS18990 (N7297_18990) 49708..49965 + 258 WP_000834292.1 hypothetical protein -
N7297_RS18995 (N7297_18995) 49970..50542 + 573 WP_000429351.1 hypothetical protein -
N7297_RS19000 (N7297_19000) 50518..50697 + 180 WP_002081921.1 hypothetical protein -
N7297_RS19005 (N7297_19005) 50714..51343 + 630 WP_002081923.1 hypothetical protein -
N7297_RS19010 (N7297_19010) 51383..51892 + 510 WP_001043199.1 hypothetical protein -
N7297_RS19015 (N7297_19015) 51973..52527 + 555 WP_000790085.1 hypothetical protein -
N7297_RS19020 (N7297_19020) 52577..53113 + 537 WP_000731981.1 hypothetical protein -
N7297_RS19025 (N7297_19025) 53736..54218 + 483 WP_001052677.1 hypothetical protein -
N7297_RS19030 (N7297_19030) 54311..54574 - 264 WP_000110863.1 hypothetical protein -
N7297_RS19035 (N7297_19035) 54675..54974 - 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
N7297_RS19040 (N7297_19040) 54974..55333 - 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7297_RS19045 (N7297_19045) 55534..56100 + 567 WP_041171756.1 hypothetical protein -
N7297_RS19050 (N7297_19050) 56149..56331 + 183 WP_000373385.1 hypothetical protein -
N7297_RS19055 (N7297_19055) 56398..57096 + 699 WP_000873190.1 hypothetical protein -
N7297_RS19060 (N7297_19060) 57235..57618 + 384 WP_000654349.1 hypothetical protein -
N7297_RS19065 (N7297_19065) 57685..58443 + 759 WP_001053129.1 hypothetical protein -
N7297_RS19070 (N7297_19070) 59513..59827 + 315 WP_000708714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71276 71276


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T259467 WP_000312250.1 NZ_CP104909:c55333-54974 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT259467 WP_001096429.1 NZ_CP104909:c54974-54675 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References