Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 5083317..5083980 Replicon chromosome
Accession NZ_CP104861
Organism Pseudomonas fragi strain D12

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N7D90_RS23305 Protein ID WP_261742515.1
Coordinates 5083615..5083980 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N7D90_RS23300 Protein ID WP_261740178.1
Coordinates 5083317..5083622 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7D90_RS23285 (N7D90_23285) 5079469..5080809 + 1341 WP_261740175.1 GntP family permease -
N7D90_RS23290 (N7D90_23290) 5080853..5082199 + 1347 WP_261740176.1 D-serine ammonia-lyase -
N7D90_RS23295 (N7D90_23295) 5082333..5083283 + 951 WP_261740177.1 DNA-binding transcriptional regulator DsdC -
N7D90_RS23300 (N7D90_23300) 5083317..5083622 - 306 WP_261740178.1 helix-turn-helix domain-containing protein Antitoxin
N7D90_RS23305 (N7D90_23305) 5083615..5083980 - 366 WP_261742515.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7D90_RS23310 (N7D90_23310) 5084198..5085481 - 1284 WP_261740179.1 OprD family porin -
N7D90_RS23315 (N7D90_23315) 5085712..5086407 - 696 WP_261740180.1 DsbA family protein -
N7D90_RS23320 (N7D90_23320) 5086791..5087897 - 1107 WP_261740181.1 agmatine deiminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(5-86)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13988.80 Da        Isoelectric Point: 6.3302

>T259387 WP_261742515.1 NZ_CP104861:c5083980-5083615 [Pseudomonas fragi]
MDWDVEYTDEFGNWWESLGEKEQVSVAASVKLLGLLGPGLRFPHCSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRCA
LLLIGGDKTGHDRWYEEYVPFAQKLYDLHLETLLEEGRKNG

Download         Length: 366 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11499.31 Da        Isoelectric Point: 7.3178

>AT259387 WP_261740178.1 NZ_CP104861:c5083622-5083317 [Pseudomonas fragi]
MAKKFAELEARMAPEARAQAQALYLQHLKELPLHELRKAQELSQEALAKKLHINQAAVSKMERRTDMYISTLRNYIQAMG
GELEIIATFADGQVKIENFAE

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References