Detailed information of TA system TA259351

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2804537..2804798
• Replicon: chromosome
• Accession: NZ_CP104856
• Organism: Enterococcus faecalis strain NY13412

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N7M47_RS13655
• Protein ID: WP_224561205.1
• Coordinates: 2804697..2804798 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2804537..2804748 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N7M47_RS13630	2800221..2801174	-	954	WP_002359060.1	siderophore ABC transporter substrate-binding protein	-
N7M47_RS13635	2801213..2801968	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
N7M47_RS13640	2801965..2802930	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
N7M47_RS13645	2802927..2803874	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
N7M47_RS13650	2804059..2804511	+	453	WP_002378807.1	YueI family protein	-
-	2804537..2804748	+	212	-	-	Antitoxin
N7M47_RS13655	2804697..2804798	-	102	WP_224561205.1	putative holin-like toxin	Toxin
N7M47_RS13660	2804989..2807259	-	2271	WP_002378809.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
N7M47_RS13665	2807430..2807936	+	507	WP_002378810.1	cysteine hydrolase family protein	-
N7M47_RS13670	2808126..2809022	+	897	WP_002365354.1	YitT family protein	-
N7M47_RS13675	2809073..2809471	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3629.37 Da
• Isoelectric Point: 4.5869

>T259351 WP_224561205.1 NZ_CP104856:c2804798-2804697 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 212 bp

>AT259351 NZ_CP104856:2804537-2804748 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGG
TTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin