Detailed information of TA system TA259348

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 619405..619631
• Replicon: chromosome
• Accession: NZ_CP104856
• Organism: Enterococcus faecalis strain NY13412

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N7M47_RS03060
• Protein ID: WP_219843903.1
• Coordinates: 619405..619515 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	619426..619631 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N7M47_RS03050	614837..617095	+	2259	WP_010716808.1	DNA helicase PcrA	-
N7M47_RS03055	617221..619251	+	2031	WP_002398122.1	NAD-dependent DNA ligase LigA	-
N7M47_RS03060	619405..619515	+	111	WP_219843903.1	putative holin-like toxin	Toxin
-	619426..619631	-	206	-	-	Antitoxin
N7M47_RS03065	619833..620138	+	306	WP_002355569.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
N7M47_RS03070	620138..621607	+	1470	WP_002398120.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-
N7M47_RS03075	621607..623037	+	1431	WP_002358703.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	-
N7M47_RS03080	623056..624144	+	1089	WP_002355572.1	diacylglycerol kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 3805.59 Da
• Isoelectric Point: 5.9482

>T259348 WP_219843903.1 NZ_CP104856:619405-619515 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 206 bp

>AT259348 NZ_CP104856:c619631-619426 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Structures

Antitoxin