Detailed information of TA system TA259131

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1062875..1063208
• Replicon: chromosome
• Accession: NZ_CP104762
• Organism: Enterococcus raffinosus strain ATCC 49464

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: N7K38_RS05395
• Protein ID: WP_010746377.1
• Coordinates: 1063065..1063208 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1062875..1063128 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N7K38_RS05365 (1059660)	1059660..1060454	+	795	WP_010746383.1	replication-relaxation family protein	-
N7K38_RS05370 (1060451)	1060451..1060765	+	315	WP_010746382.1	hypothetical protein	-
N7K38_RS05375 (1061157)	1061157..1061432	+	276	WP_010746381.1	hypothetical protein	-
N7K38_RS05380 (1061456)	1061456..1061791	+	336	WP_010746380.1	hypothetical protein	-
N7K38_RS05385 (1061920)	1061920..1062306	+	387	WP_010746379.1	hypothetical protein	-
N7K38_RS05390 (1062381)	1062381..1062845	+	465	WP_010746378.1	single-stranded DNA-binding protein	-
- (1062875)	1062875..1063128	+	254	NuclAT_0	-	Antitoxin
N7K38_RS05395 (1063065)	1063065..1063208	-	144	WP_010746377.1	putative holin-like toxin	Toxin
N7K38_RS05400 (1063246)	1063246..1063506	-	261	WP_162531353.1	hypothetical protein	-
N7K38_RS05405 (1063550)	1063550..1064062	+	513	WP_010746376.1	hypothetical protein	-
N7K38_RS05410 (1064064)	1064064..1064237	+	174	WP_010746375.1	hypothetical protein	-
N7K38_RS05415 (1064234)	1064234..1064731	+	498	WP_010746374.1	DnaJ domain-containing protein	-
N7K38_RS05420 (1064842)	1064842..1065060	+	219	WP_010746373.1	hypothetical protein	-
N7K38_RS05425 (1065050)	1065050..1065229	+	180	WP_010746372.1	hypothetical protein	-
N7K38_RS05430 (1065245)	1065245..1065433	+	189	WP_010746371.1	hypothetical protein	-
N7K38_RS05435 (1065475)	1065475..1066329	+	855	WP_010746370.1	DNA/RNA non-specific endonuclease	-
N7K38_RS05440 (1066326)	1066326..1066457	+	132	WP_010746369.1	hypothetical protein	-
N7K38_RS05445 (1066521)	1066521..1066769	+	249	WP_000447966.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
N7K38_RS05450 (1066771)	1066771..1067058	+	288	WP_000179848.1	Txe/YoeB family addiction module toxin	-
N7K38_RS05455 (1067299)	1067299..1067538	+	240	WP_010746368.1	BRCT domain-containing protein	-
N7K38_RS05460 (1067773)	1067773..1068018	+	246	WP_010746367.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	ebpC	1028724..1118411	89687

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5227.35 Da
• Isoelectric Point: 10.2858

>T259131 WP_010746377.1 NZ_CP104762:c1063208-1063065 [Enterococcus raffinosus]
MNVLPKSKERKCLLSVSEGLQLMIAFGGFTLTLITTIVAILNYKDKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 254 bp

>AT259131 NZ_CP104762:1062875-1063128 [Enterococcus raffinosus]
CACCACCACCACCGTTTAGGAGCGCATGAAAAAAAGAAAGGCTTCCGCCTTTCTTCTCGCTCAAAATGTGGTATAATGAC
TATGTAAAGAGGACGTACTAGTAATACGCCCTCAATGATAGCACCGCTAAAGACGGTGGCAGATTTATATTCTAATTAAA
AAATAGTCGTCCACCTGCTAAAGCTGACGGCTATTTTTTGTCTTTATAGTTCAGAATTGCAACAATGGTTGTTATTAAGG
TTAGCGTAAAGCCA

Structures

Antitoxin