Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 499568..500070 Replicon chromosome
Accession NZ_CP104757
Organism Pectobacterium aroidearum strain QJ021

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag N5056_RS02290 Protein ID WP_039282578.1
Coordinates 499568..499822 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag N5056_RS02295 Protein ID WP_039324900.1
Coordinates 499819..500070 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5056_RS02270 (N5056_02270) 494705..495967 - 1263 WP_181829903.1 L-rhamnose isomerase -
N5056_RS02275 (N5056_02275) 495964..497454 - 1491 WP_181829902.1 rhamnulokinase -
N5056_RS02280 (N5056_02280) 497790..498629 + 840 WP_012773133.1 HTH-type transcriptional activator RhaS -
N5056_RS02285 (N5056_02285) 498654..499508 + 855 WP_181829901.1 helix-turn-helix domain-containing protein -
N5056_RS02290 (N5056_02290) 499568..499822 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
N5056_RS02295 (N5056_02295) 499819..500070 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
N5056_RS02300 (N5056_02300) 500146..501855 - 1710 WP_181829900.1 ABC transporter ATP-binding protein -
N5056_RS02305 (N5056_02305) 501852..502718 - 867 WP_181829899.1 ABC transporter permease -
N5056_RS02310 (N5056_02310) 502711..503670 - 960 WP_181829898.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T259115 WP_039282578.1 NZ_CP104757:c499822-499568 [Pectobacterium aroidearum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT259115 WP_039324900.1 NZ_CP104757:c500070-499819 [Pectobacterium aroidearum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References