Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4369052..4369887 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag NAL19_RS19640 Protein ID WP_225086048.1
Coordinates 4369052..4369537 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag NAL19_RS19645 Protein ID WP_225086049.1
Coordinates 4369543..4369887 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS19620 (NAL19_4215) 4364604..4366037 - 1434 WP_263058208.1 FtsX-like permease family protein -
NAL19_RS19625 (NAL19_4216) 4366034..4366726 - 693 WP_225086045.1 ABC transporter ATP-binding protein -
NAL19_RS19630 (NAL19_4217) 4366735..4367214 - 480 WP_263058209.1 hypothetical protein -
NAL19_RS19635 (NAL19_4218) 4367227..4368972 - 1746 WP_225086047.1 alkaline phosphatase -
NAL19_RS19640 (NAL19_4219) 4369052..4369537 - 486 WP_225086048.1 type II toxin-antitoxin system YhaV family toxin Toxin
NAL19_RS19645 (NAL19_4220) 4369543..4369887 - 345 WP_225086049.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NAL19_RS19650 (NAL19_4221) 4370086..4373211 - 3126 WP_263058210.1 multidrug efflux RND transporter permease AcrD -
NAL19_RS19655 (NAL19_4222) 4373521..4374288 - 768 WP_225086051.1 pimeloyl-ACP methyl ester esterase BioH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 18770.60 Da        Isoelectric Point: 9.8930

>T259091 WP_225086048.1 NZ_CP104733:c4369537-4369052 [Pectobacterium sp. F1-1]
MVDKRVINGWQLFTHPCFDVQFESLIVEVEQLRKKHPESYQKKQATKLLAAIVKVIRTEICGDPSQTKFRQGDTLGEGNK
HWFRAKFLGQYRLFFRYSEKHKTIILAWVNDSDTKRAYGDQHDAYKVFSGMLASGNPPGDWKQLLAESYKETMLTQMLVR
P

Download         Length: 486 bp

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12802.40 Da        Isoelectric Point: 4.5491

>AT259091 WP_225086049.1 NZ_CP104733:c4369887-4369543 [Pectobacterium sp. F1-1]
MFNLKSADVLLRADSRLTARSQTTIPSSVRDAMNLQPGEYIHYSVLPGGQVLISRREEAVDDDPVIHRFLHFLAEDMQHH
PENIKPFDQSLMSRASVLTAGMDIDLDAPLTDDE

Download         Length: 345 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References