Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 513742..514244 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag NAL19_RS02320 Protein ID WP_039282578.1
Coordinates 513742..513996 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag NAL19_RS02325 Protein ID WP_039324900.1
Coordinates 513993..514244 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS02300 (NAL19_503) 508897..510159 - 1263 WP_225086718.1 L-rhamnose isomerase -
NAL19_RS02305 (NAL19_504) 510156..511646 - 1491 WP_263058647.1 rhamnulokinase -
NAL19_RS02310 (NAL19_506) 511982..512821 + 840 WP_225086720.1 HTH-type transcriptional activator RhaS -
NAL19_RS02315 (NAL19_507) 512846..513700 + 855 WP_225086721.1 helix-turn-helix domain-containing protein -
NAL19_RS02320 (NAL19_508) 513742..513996 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
NAL19_RS02325 (NAL19_509) 513993..514244 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
NAL19_RS02330 (NAL19_510) 514320..516023 - 1704 WP_225086723.1 ABC transporter ATP-binding protein -
NAL19_RS02335 (NAL19_511) 516020..516884 - 865 Protein_451 ABC transporter permease -
NAL19_RS02340 (NAL19_513) 516877..517836 - 960 WP_012773138.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T259084 WP_039282578.1 NZ_CP104733:c513996-513742 [Pectobacterium sp. F1-1]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT259084 WP_039324900.1 NZ_CP104733:c514244-513993 [Pectobacterium sp. F1-1]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References