259069

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1623318..1623940 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N5P21_RS07170 Protein ID WP_261747808.1
Coordinates 1623626..1623940 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N5P21_RS07165 Protein ID WP_261747807.1
Coordinates 1623318..1623623 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS07145 (N5P21_07145) 1618943..1619455 - 513 WP_074979044.1 RDD family protein -
N5P21_RS07150 (N5P21_07150) 1619624..1621165 + 1542 WP_261747804.1 cyclic diguanylate phosphodiesterase -
N5P21_RS07155 (N5P21_07155) 1621259..1621597 - 339 WP_261747805.1 hypothetical protein -
N5P21_RS07160 (N5P21_07160) 1621688..1623133 - 1446 WP_261747806.1 SulP family inorganic anion transporter -
N5P21_RS07165 (N5P21_07165) 1623318..1623623 - 306 WP_261747807.1 helix-turn-helix domain-containing protein Antitoxin
N5P21_RS07170 (N5P21_07170) 1623626..1623940 - 315 WP_261747808.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5P21_RS07175 (N5P21_07175) 1624235..1625137 + 903 WP_261747809.1 site-specific integrase -
N5P21_RS07180 (N5P21_07180) 1625164..1625982 - 819 WP_116423177.1 hypothetical protein -
N5P21_RS07185 (N5P21_07185) 1625957..1626118 - 162 WP_181925962.1 hypothetical protein -
N5P21_RS07190 (N5P21_07190) 1626833..1627072 - 240 WP_261748818.1 hypothetical protein -
N5P21_RS07195 (N5P21_07195) 1627112..1627636 + 525 Protein_1420 hypothetical protein -
N5P21_RS07200 (N5P21_07200) 1627786..1628439 + 654 WP_261747810.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-72)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11808.53 Da        Isoelectric Point: 9.4819

>T259069 WP_261747808.1 NZ_CP104727:c1623940-1623626 [Pseudomonas citronellolis]
MIFIETPVFTRQILELVDDETYRRLQEDLTLHPDAGTVIAGTGGVRKIRIAANGHGKRGGARVIYYHFVSASHIAFLLAY
DKATQEDLTANQKKVLRQIIENWR

Download         Length: 315 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11267.76 Da        Isoelectric Point: 7.3221

>AT259069 WP_261747807.1 NZ_CP104727:c1623623-1623318 [Pseudomonas citronellolis]
MDKELFAELVESVTQMDEIVRGERQPSREFHVDAVKVREIRRATGLSQAKFAEKINVAVGTLRNWEQGRRDPEGPARALL
QAIHNDPVHVLAALNGGPSKN

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References