Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 639393..640048 Replicon chromosome
Accession NZ_CP104582
Organism Pseudomonas sp. GD03919

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N5O87_RS03020 Protein ID WP_058136484.1
Coordinates 639704..640048 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N5O87_RS03015 Protein ID WP_027600721.1
Coordinates 639393..639707 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O87_RS02980 (N5O87_02980) 635716..635955 - 240 WP_058136487.1 entry exclusion lipoprotein TrbK -
N5O87_RS02985 (N5O87_02985) 635966..636745 - 780 WP_279532051.1 P-type conjugative transfer protein TrbJ -
N5O87_RS02990 (N5O87_02990) 636726..637118 - 393 WP_069734902.1 hypothetical protein -
N5O87_RS02995 (N5O87_02995) 637115..637387 - 273 WP_279532052.1 hypothetical protein -
N5O87_RS03000 (N5O87_03000) 637384..637776 - 393 WP_128669104.1 TraK family protein -
N5O87_RS03005 (N5O87_03005) 637794..638648 - 855 WP_279532053.1 helix-turn-helix domain-containing protein -
N5O87_RS03010 (N5O87_03010) 638648..638875 - 228 WP_071579492.1 helix-turn-helix domain-containing protein -
N5O87_RS03015 (N5O87_03015) 639393..639707 - 315 WP_027600721.1 transcriptional regulator Antitoxin
N5O87_RS03020 (N5O87_03020) 639704..640048 - 345 WP_058136484.1 hypothetical protein Toxin
N5O87_RS03025 (N5O87_03025) 640096..641169 - 1074 WP_058136483.1 site-specific integrase -
N5O87_RS03035 (N5O87_03035) 641517..643250 - 1734 WP_279532054.1 group II intron reverse transcriptase/maturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 644087..645358 1271


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13407.38 Da        Isoelectric Point: 9.9930

>T258471 WP_058136484.1 NZ_CP104582:c640048-639704 [Pseudomonas sp. GD03919]
MKALFVELPPFERHRADYLDDEAFRSFQRLLMKNPEAGDVIQGTGGLRKIRFADERRQKGKRGGIRVIYYWWLGGAQFWL
FTLYGKDVQDDLNEQQKKLLKQLLQAEIDARTTS

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12021.81 Da        Isoelectric Point: 6.4735

>AT258471 WP_027600721.1 NZ_CP104582:c639707-639393 [Pseudomonas sp. GD03919]
MKRDIFAELVEGFEALEDERQGKVTLRSHKVQLPELCEVSSEELVEIRQKLNMSRPVFAMYLRTNPRTLENWEQGRAKPN
AQATTLIRLVQKYPETVEHLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References