258463

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 900166..900983 Replicon chromosome
Accession NZ_CP104581
Organism Delftia tsuruhatensis strain GD03927

Toxin (Protein)


Gene name yhaV Uniprot ID A0A072THA9
Locus tag N5O86_RS04045 Protein ID WP_043790975.1
Coordinates 900166..900657 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag N5O86_RS04050 Protein ID WP_016448384.1
Coordinates 900654..900983 (-) Length 110 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O86_RS04015 (N5O86_04015) 895304..895789 + 486 WP_026062693.1 cobalamin biosynthesis protein -
N5O86_RS04020 (N5O86_04020) 895786..896664 + 879 WP_279494183.1 precorrin-4 C(11)-methyltransferase -
N5O86_RS04025 (N5O86_04025) 896661..897458 + 798 WP_279494184.1 precorrin-6A synthase (deacetylating) -
N5O86_RS04030 (N5O86_04030) 897522..897851 + 330 WP_013800515.1 DHCW motif cupin fold protein -
N5O86_RS04035 (N5O86_04035) 898127..899524 + 1398 WP_017406579.1 chloride channel protein -
N5O86_RS04040 (N5O86_04040) 899639..900151 + 513 WP_016448386.1 MgtC/SapB family protein -
N5O86_RS04045 (N5O86_04045) 900166..900657 - 492 WP_043790975.1 type II toxin-antitoxin system YhaV family toxin Toxin
N5O86_RS04050 (N5O86_04050) 900654..900983 - 330 WP_016448384.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
N5O86_RS04055 (N5O86_04055) 901081..903324 - 2244 WP_279494187.1 TonB-dependent receptor -
N5O86_RS04060 (N5O86_04060) 903435..903839 - 405 WP_046988681.1 hypothetical protein -
N5O86_RS04065 (N5O86_04065) 903868..904530 - 663 WP_046988682.1 pyridoxamine 5'-phosphate oxidase family protein -
N5O86_RS04070 (N5O86_04070) 904601..905431 + 831 WP_141835639.1 helix-turn-helix transcriptional regulator -
N5O86_RS04075 (N5O86_04075) 905521..905790 + 270 WP_012207631.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(16-152)

Antitoxin

(8-107)


Sequences


Toxin        


Download         Length: 164 a.a.        Molecular weight: 18801.33 Da        Isoelectric Point: 9.9304

>T258463 WP_043790975.1 NZ_CP104581:c900657-900166 [Delftia tsuruhatensis]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSHEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTRRAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAESPPPDSQ
PHA

Download         Length: 492 bp


Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12062.53 Da        Isoelectric Point: 4.1858

>AT258463 WP_016448384.1 NZ_CP104581:c900983-900654 [Delftia tsuruhatensis]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A072THA9


Antitoxin

Source ID Structure

References