Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2091098..2091600 Replicon chromosome
Accession NZ_CP104580
Organism Stutzerimonas stutzeri strain GD04120

Toxin (Protein)


Gene name yoeB Uniprot ID A0A235EZL9
Locus tag N5O82_RS10155 Protein ID WP_075117074.1
Coordinates 2091346..2091600 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A235F1E0
Locus tag N5O82_RS10150 Protein ID WP_075117073.1
Coordinates 2091098..2091349 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O82_RS10120 (N5O82_10115) 2086573..2087463 + 891 WP_125885723.1 ATP-binding protein -
N5O82_RS10125 (N5O82_10120) 2087526..2088203 - 678 WP_045158414.1 glutathione S-transferase family protein -
N5O82_RS10130 (N5O82_10125) 2088258..2089025 - 768 WP_017243998.1 hypothetical protein -
N5O82_RS10145 (N5O82_10140) 2089633..2090865 + 1233 Protein_1998 tyrosine-type recombinase/integrase -
N5O82_RS10150 (N5O82_10145) 2091098..2091349 + 252 WP_075117073.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
N5O82_RS10155 (N5O82_10150) 2091346..2091600 + 255 WP_075117074.1 Txe/YoeB family addiction module toxin Toxin
N5O82_RS10160 (N5O82_10155) 2091817..2092206 + 390 WP_094267730.1 DUF3742 family protein -
N5O82_RS10165 (N5O82_10160) 2092214..2093734 - 1521 WP_102053794.1 conjugal transfer protein TraG N-terminal domain-containing protein -
N5O82_RS10170 (N5O82_10165) 2093750..2094100 - 351 WP_094267732.1 hypothetical protein -
N5O82_RS10175 (N5O82_10170) 2094414..2095211 + 798 WP_102053793.1 hypothetical protein -
N5O82_RS10180 (N5O82_10175) 2095219..2096082 - 864 WP_094267734.1 integrase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.65 Da        Isoelectric Point: 9.4089

>T258459 WP_075117074.1 NZ_CP104580:2091346-2091600 [Stutzerimonas stutzeri]
VKLIWSEQAWDDYLYWQEADKRMVKKLNELIKETRRTPFEGKGKPEPLRHNLAGFWSRRITAEHRFVYSVTDEALLIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9391.61 Da        Isoelectric Point: 4.5843

>AT258459 WP_075117073.1 NZ_CP104580:2091098-2091349 [Stutzerimonas stutzeri]
MRTISYTEARQNLSATMVQTVEDRVPTLITRQNGEACVLMSLEEYNALEETAYLLRSPANARRLMDSIDSLKRGQGVERD
IAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A235EZL9

Antitoxin

Source ID Structure
AlphaFold DB A0A235F1E0

References