Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2518907..2519091 Replicon chromosome
Accession NZ_CP104559
Organism Staphylococcus aureus strain SA2107

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag N4T05_RS12695 Protein ID WP_000482647.1
Coordinates 2518984..2519091 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2518907..2518967 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4T05_RS12675 2514493..2514660 - 168 WP_031785511.1 hypothetical protein -
N4T05_RS12680 2514891..2516624 - 1734 WP_000488492.1 ABC transporter ATP-binding protein -
N4T05_RS12685 2516673..2518412 - 1740 WP_234739903.1 ABC transporter ATP-binding protein -
N4T05_RS12690 2518790..2518957 - 168 WP_000301894.1 hypothetical protein -
- 2518907..2518967 + 61 - - Antitoxin
N4T05_RS12695 2518984..2519091 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
N4T05_RS12700 2519225..2519611 - 387 WP_000779354.1 flippase GtxA -
N4T05_RS12705 2519879..2521021 + 1143 WP_103215193.1 glycerate kinase -
N4T05_RS12710 2521081..2521740 + 660 WP_000831298.1 membrane protein -
N4T05_RS12715 2521920..2523131 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
N4T05_RS12720 2523254..2523727 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T258444 WP_000482647.1 NZ_CP104559:c2519091-2518984 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT258444 NZ_CP104559:2518907-2518967 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References