Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4188277..4188774 | Replicon | chromosome |
Accession | NZ_CP104536 | ||
Organism | Escherichia coli strain E3 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | N5O72_RS20315 | Protein ID | WP_001173343.1 |
Coordinates | 4188277..4188450 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | J7RC38 |
Locus tag | N5O72_RS20320 | Protein ID | WP_001425728.1 |
Coordinates | 4188478..4188774 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N5O72_RS20305 (4184947) | 4184947..4186404 | + | 1458 | WP_000856841.1 | dipeptide/tripeptide permease DtpC | - |
N5O72_RS20310 (4186641) | 4186641..4188158 | + | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
N5O72_RS20315 (4188277) | 4188277..4188450 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
N5O72_RS20320 (4188478) | 4188478..4188774 | - | 297 | WP_001425728.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
N5O72_RS20325 (4189001) | 4189001..4189273 | - | 273 | WP_000405647.1 | GNAT family N-acetyltransferase | - |
N5O72_RS20330 (4189285) | 4189285..4189515 | - | 231 | WP_000371700.1 | 4Fe-4S mono-cluster protein YjdI | - |
N5O72_RS20335 (4189696) | 4189696..4191327 | + | 1632 | WP_001216487.1 | sensor histidine kinase | - |
N5O72_RS20340 (4191324) | 4191324..4192043 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 4179423..4188774 | 9351 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | J7RC38 |