258332

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4125885..4126143 Replicon chromosome
Accession NZ_CP104533
Organism Escherichia coli strain E10

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag N5O77_RS20470 Protein ID WP_000809168.1
Coordinates 4125991..4126143 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4125885..4125942 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O77_RS20455 4121717..4122976 - 1260 WP_000494924.1 hypothetical protein -
N5O77_RS20460 4123105..4124598 - 1494 WP_001350775.1 sulfatase-like hydrolase/transferase -
N5O77_RS20465 4124618..4125379 - 762 WP_001274823.1 outer membrane protein OmpK -
- 4125885..4125942 - 58 - - Antitoxin
N5O77_RS20470 4125991..4126143 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
N5O77_RS20475 4126248..4127378 - 1131 WP_001118464.1 molecular chaperone DnaJ -
N5O77_RS20480 4127467..4129383 - 1917 WP_000516135.1 molecular chaperone DnaK -
N5O77_RS20485 4129755..4130159 + 405 WP_000843687.1 DUF2541 family protein -
N5O77_RS20490 4130185..4130898 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T258332 WP_000809168.1 NZ_CP104533:4125991-4126143 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT258332 NZ_CP104533:c4125942-4125885 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References