Detailed information of TA system TA258317

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 178478..178700
• Replicon: chromosome
• Accession: NZ_CP104533
• Organism: Escherichia coli strain E10

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: N5O77_RS00840
• Protein ID: WP_001295224.1
• Coordinates: 178593..178700 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	178478..178536 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5O77_RS00815	173867..174850	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
N5O77_RS00820	174847..175851	+	1005	WP_261175560.1	dipeptide ABC transporter ATP-binding subunit DppF	-
N5O77_RS00825	175881..177152	-	1272	WP_001332306.1	aromatic amino acid transport family protein	-
N5O77_RS00830	177628..177735	+	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O77_RS00835	178110..178217	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	178478..178536	-	59	-	-	Antitoxin
N5O77_RS00840	178593..178700	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
N5O77_RS00845	178786..180465	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
N5O77_RS00850	180462..180653	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
N5O77_RS00855	180650..182221	-	1572	WP_001204957.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
N5O77_RS00860	182494..182682	+	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-
N5O77_RS00865	182694..183446	+	753	WP_000279545.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T258317 WP_001295224.1 NZ_CP104533:178593-178700 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT258317 NZ_CP104533:c178536-178478 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin