Detailed information of TA system TA258287

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4660380..4660602
• Replicon: chromosome
• Accession: NZ_CP104523
• Organism: Escherichia coli strain E7

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: N5O80_RS22755
• Protein ID: WP_001295224.1
• Coordinates: 4660380..4660487 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4660536..4660602 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5O80_RS22730	4655664..4657235	+	1572	WP_001204944.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
N5O80_RS22735	4657232..4657423	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
N5O80_RS22740	4657420..4659099	+	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
N5O80_RS22745	4659214..4659672	-	459	WP_000526135.1	IS200/IS605-like element IS200C family transposase	-
N5O80_RS22750	4659897..4660004	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O80_RS22755	4660380..4660487	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4660536..4660602	+	67	-	-	Antitoxin
N5O80_RS22760	4660863..4660970	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O80_RS22765	4661346..4661453	-	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O80_RS22770	4661929..4663200	+	1272	WP_001318103.1	aromatic amino acid transport family protein	-
N5O80_RS22775	4663230..4664234	-	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
N5O80_RS22780	4664231..4665214	-	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	4659214..4659672	458

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T258287 WP_001295224.1 NZ_CP104523:c4660487-4660380 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT258287 NZ_CP104523:4660536-4660602 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin