Detailed information of TA system TA258259

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4526162..4526384
• Replicon: chromosome
• Accession: NZ_CP104521
• Organism: Escherichia coli strain E5

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A829L523
• Locus tag: N5O78_RS21955
• Protein ID: WP_000170738.1
• Coordinates: 4526162..4526269 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4526318..4526384 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5O78_RS21925	4521191..4522762	+	1572	WP_001204944.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
N5O78_RS21930	4522759..4522950	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
N5O78_RS21935	4522947..4524626	+	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
N5O78_RS21940	4524713..4524820	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O78_RS21945	4525196..4525303	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O78_RS21950	4525679..4525786	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
N5O78_RS21955	4526162..4526269	-	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4526318..4526384	+	67	-	-	Antitoxin
N5O78_RS21960	4526745..4528016	+	1272	WP_001318103.1	aromatic amino acid transport family protein	-
N5O78_RS21965	4528046..4529050	-	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
N5O78_RS21970	4529047..4530030	-	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-
N5O78_RS21975	4530041..4530943	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3864.67 Da
• Isoelectric Point: 9.0157

>T258259 WP_000170738.1 NZ_CP104521:c4526269-4526162 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT258259 NZ_CP104521:4526318-4526384 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A829L523

Antitoxin