Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3972774..3973032 Replicon chromosome
Accession NZ_CP104503
Organism Escherichia coli strain E1

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag N5O81_RS19270 Protein ID WP_000809168.1
Coordinates 3972774..3972926 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3972975..3973032 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O81_RS19250 3968019..3968732 - 714 WP_001102393.1 acidic protein MsyB -
N5O81_RS19255 3968758..3969162 - 405 WP_000843692.1 DUF2541 family protein -
N5O81_RS19260 3969534..3971450 + 1917 WP_000516135.1 molecular chaperone DnaK -
N5O81_RS19265 3971539..3972669 + 1131 WP_001118464.1 molecular chaperone DnaJ -
N5O81_RS19270 3972774..3972926 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3972975..3973032 + 58 - - Antitoxin
N5O81_RS19275 3973541..3974302 + 762 WP_001274832.1 outer membrane protein OmpK -
N5O81_RS19280 3974322..3975815 + 1494 WP_001350365.1 sulfatase-like hydrolase/transferase -
N5O81_RS19285 3975944..3977203 + 1260 WP_000494929.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T258173 WP_000809168.1 NZ_CP104503:c3972926-3972774 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT258173 NZ_CP104503:3972975-3973032 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References