258041

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 405176..405714 Replicon chromosome
Accession NZ_CP104479
Organism Salmonella enterica strain SalSpp_sample_09_No.5

Toxin (Protein)


Gene name yafQ Uniprot ID A0A3V8R2L4
Locus tag N4G50_RS01860 Protein ID WP_023231798.1
Coordinates 405439..405714 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A7U1KUN1
Locus tag N4G50_RS01855 Protein ID WP_000729714.1
Coordinates 405176..405436 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4G50_RS01840 (400929) 400929..402482 + 1554 WP_024156903.1 TROVE domain-containing protein -
N4G50_RS01845 (402830) 402830..404044 + 1215 WP_024156904.1 RNA-splicing ligase RtcB -
N4G50_RS01850 (404048) 404048..405067 + 1020 WP_023238362.1 RNA 3'-terminal phosphate cyclase -
N4G50_RS01855 (405176) 405176..405436 + 261 WP_000729714.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N4G50_RS01860 (405439) 405439..405714 + 276 WP_023231798.1 type II toxin-antitoxin system YafQ family toxin Toxin
N4G50_RS01865 (405802) 405802..408507 - 2706 WP_000907043.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10645.22 Da        Isoelectric Point: 8.8623

>T258041 WP_023231798.1 NZ_CP104479:405439-405714 [Salmonella enterica]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDYPLQGSYSGYRDAHIGPDWILIDKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9445.82 Da        Isoelectric Point: 4.6028

>AT258041 WP_000729714.1 NZ_CP104479:405176-405436 [Salmonella enterica]
MAANALVRARIDETLKNQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V8R2L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7U1KUN1

References