Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3793908..3794364 Replicon chromosome
Accession NZ_CP104323
Organism Stenotrophomonas maltophilia strain ACYCc.3B

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag K7564_RS20460 Protein ID WP_276577093.1
Coordinates 3794218..3794364 (-) Length 49 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag K7564_RS17630 Protein ID WP_197575533.1
Coordinates 3793908..3794207 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7564_RS17610 (K7564_17610) 3789335..3790528 + 1194 WP_227864094.1 pyridoxal phosphate-dependent aminotransferase -
K7564_RS17615 (K7564_17615) 3790647..3792743 - 2097 WP_126411375.1 prolyl oligopeptidase family serine peptidase -
K7564_RS17620 (K7564_17620) 3792813..3793136 - 324 WP_049439992.1 hypothetical protein -
K7564_RS17625 (K7564_17625) 3793265..3793867 + 603 WP_014648471.1 lipocalin family protein -
K7564_RS17630 (K7564_17630) 3793908..3794207 - 300 WP_197575533.1 HigA family addiction module antitoxin Antitoxin
K7564_RS20460 3794218..3794364 - 147 WP_276577093.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7564_RS17640 (K7564_17640) 3794702..3795391 - 690 WP_197575531.1 methionine ABC transporter permease -
K7564_RS17645 (K7564_17645) 3795388..3796395 - 1008 WP_014648473.1 methionine ABC transporter ATP-binding protein -
K7564_RS17650 (K7564_17650) 3796606..3797502 - 897 WP_014648474.1 DMT family transporter -
K7564_RS17655 (K7564_17655) 3797658..3798140 + 483 WP_006471121.1 YajQ family cyclic di-GMP-binding protein -
K7564_RS17660 (K7564_17660) 3798242..3798808 + 567 WP_049406028.1 DUF1415 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-48)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-87)


Sequences

Toxin        


Download         Length: 49 a.a.        Molecular weight: 5524.11 Da        Isoelectric Point: 5.6689

>T257584 WP_276577093.1 NZ_CP104323:c3794364-3794218 [Stenotrophomonas maltophilia]
MRSPPGNRLEALSGDRRGQYSLRINDQWRLCFTWTDGGADAVEIVDYH

Download         Length: 147 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10943.62 Da        Isoelectric Point: 10.9753

>AT257584 WP_197575533.1 NZ_CP104323:c3794207-3793908 [Stenotrophomonas maltophilia]
MKRPHNGMRAIHPGEILREEFLLPLSLSVNALAKALDVPATRLHAIVHGQRSISADTAARLARHFGGDAASWLAMQAAYD
LKTLPTRSEIERRVQPREA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References