257349

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1718974..1719566 Replicon chromosome
Accession NZ_CP104158
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N2601_RS08425 Protein ID WP_104823382.1
Coordinates 1719285..1719566 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag N2601_RS08420 Protein ID WP_104825122.1
Coordinates 1718974..1719273 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS08410 (N2601_08410) 1714583..1715182 - 600 WP_104823380.1 dimethylsulfonioproprionate lyase family protein -
N2601_RS08415 (N2601_08415) 1715179..1718949 - 3771 WP_104823381.1 cobaltochelatase subunit CobN -
N2601_RS08420 (N2601_08420) 1718974..1719273 - 300 WP_104825122.1 HigA family addiction module antitoxin Antitoxin
N2601_RS08425 (N2601_08425) 1719285..1719566 - 282 WP_104823382.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2601_RS08430 (N2601_08430) 1719624..1720673 - 1050 WP_104825123.1 cobalamin biosynthesis protein CobW -
N2601_RS08435 (N2601_08435) 1720679..1721206 - 528 WP_104823383.1 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -
N2601_RS08440 (N2601_08440) 1721929..1723725 + 1797 WP_104823384.1 chloride channel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(16-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10517.96 Da        Isoelectric Point: 8.9312

>T257349 WP_104823382.1 NZ_CP104158:c1719566-1719285 [Rhizobium tropici]
VIVSYKGKFAEAVASGNVPKGFPADLVRSAQRKLTILNYAVVLDDLRSPPGNRLERLQGDRSGQYSIRINDQWRICFLWT
EAGPRDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10970.68 Da        Isoelectric Point: 5.6939

>AT257349 WP_104825122.1 NZ_CP104158:c1719273-1718974 [Rhizobium tropici]
MTETKLPPIHPGEILREEYLKPLTMSAGALAKHLNVPRTRIERLVSEDTGVTPDTALRLARFFSTTPDFWMAMQTGYDLA
IAQAEKSDVFAAIKPLEAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References