Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 60472..60997 Replicon plasmid pWSM1274_2
Accession NZ_CP104140
Organism Rhizobium leguminosarum bv. viciae strain WSM1274

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N2600_RS30025 Protein ID WP_260299627.1
Coordinates 60725..60997 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N2600_RS30020 Protein ID WP_260111936.1
Coordinates 60472..60723 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2600_RS30010 (N2600_30010) 57153..58496 - 1344 WP_260111934.1 adenylate/guanylate cyclase domain-containing protein -
N2600_RS30015 (N2600_30015) 59001..60338 + 1338 WP_260299626.1 nucleotide sugar dehydrogenase -
N2600_RS30020 (N2600_30020) 60472..60723 + 252 WP_260111936.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N2600_RS30025 (N2600_30025) 60725..60997 + 273 WP_260299627.1 Txe/YoeB family addiction module toxin Toxin
N2600_RS30030 (N2600_30030) 61052..62227 - 1176 WP_162115193.1 DUF3095 domain-containing protein -
N2600_RS30035 (N2600_30035) 62452..62931 + 480 WP_260299628.1 class I SAM-dependent methyltransferase -
N2600_RS30040 (N2600_30040) 63057..64847 - 1791 WP_260299629.1 ABC transporter ATP-binding protein -
N2600_RS30045 (N2600_30045) 65263..65718 - 456 WP_222386857.1 Rrf2 family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..423083 423083


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10820.46 Da        Isoelectric Point: 8.4756

>T257332 WP_260299627.1 NZ_CP104140:60725-60997 [Rhizobium leguminosarum bv. viciae]
MKLLWTPNSWEEYEYWQKSDQKMVEKINELLKDTKRSPFKVLGKPEPLKGDLSGFWSRRILGEHRLVYCVTGKGSDQELE
IIQCRFHYEK

Download         Length: 273 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9303.61 Da        Isoelectric Point: 5.6513

>AT257332 WP_260111936.1 NZ_CP104140:60472-60723 [Rhizobium leguminosarum bv. viciae]
MAHVRLTEFRQNIATYFDQVLSSRAPLLVTRQGSEAMVLVAEGEYESMQEMLHLLSTPANSARLRESIGQLRKGQVVESD
PTL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References