Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3609813..3610467 Replicon chromosome
Accession NZ_CP104045
Organism Pseudomonas sp. FJ2-5-13

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N2A98_RS15820 Protein ID WP_003192123.1
Coordinates 3609813..3610163 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A1T1HTP3
Locus tag N2A98_RS15825 Protein ID WP_044274604.1
Coordinates 3610153..3610467 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2A98_RS15810 (N2A98_15830) 3606571..3608103 + 1533 WP_014718913.1 NADH-quinone oxidoreductase subunit M -
N2A98_RS15815 (N2A98_15835) 3608111..3609574 + 1464 WP_003192122.1 NADH-quinone oxidoreductase subunit NuoN -
N2A98_RS15820 (N2A98_15840) 3609813..3610163 + 351 WP_003192123.1 toxin Toxin
N2A98_RS15825 (N2A98_15845) 3610153..3610467 + 315 WP_044274604.1 hypothetical protein Antitoxin
N2A98_RS15830 (N2A98_15850) 3610529..3611281 - 753 WP_044274605.1 outer membrane beta-barrel protein -
N2A98_RS15835 (N2A98_15855) 3611407..3612240 - 834 WP_044274606.1 arylamine N-acetyltransferase -
N2A98_RS15840 (N2A98_15860) 3612361..3612597 + 237 WP_003192128.1 hypothetical protein -
N2A98_RS15845 (N2A98_15865) 3612628..3612828 - 201 WP_044274607.1 DUF6021 family protein -
N2A98_RS15850 (N2A98_15870) 3612841..3613020 - 180 WP_044274608.1 hypothetical protein -
N2A98_RS15855 (N2A98_15875) 3613135..3613656 + 522 WP_044274609.1 DUF3087 family protein -
N2A98_RS15860 (N2A98_15880) 3613786..3614499 + 714 WP_228391104.1 carbonic anhydrase -
N2A98_RS15865 (N2A98_15885) 3614506..3614592 - 87 Protein_3129 outer membrane lipoprotein carrier protein LolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13826.71 Da        Isoelectric Point: 9.7551

>T257089 WP_003192123.1 NZ_CP104045:3609813-3610163 [Pseudomonas sp. FJ2-5-13]
MDALFIELPAFERHRRDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQNDLTPQHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11783.63 Da        Isoelectric Point: 10.9218

>AT257089 WP_044274604.1 NZ_CP104045:3610153-3610467 [Pseudomonas sp. FJ2-5-13]
MKREIFSELVEGFDALADERQGKITLRTHKAHLNKLAPLRADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1T1HTP3

References