Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 240809..241410 Replicon chromosome
Accession NZ_CP104044
Organism Pseudomonas sp. SD17-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag N0B28_RS01100 Protein ID WP_275729910.1
Coordinates 241096..241410 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag N0B28_RS01095 Protein ID WP_054915914.1
Coordinates 240809..241096 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0B28_RS01070 (N0B28_01070) 236223..236705 - 483 WP_054915912.1 ATP-dependent zinc protease -
N0B28_RS01075 (N0B28_01075) 236815..237216 + 402 WP_043861624.1 S4 domain-containing protein -
N0B28_RS01080 (N0B28_01080) 237213..238016 - 804 WP_078481608.1 phosphatase PAP2 family protein -
N0B28_RS01085 (N0B28_01085) 238122..239024 + 903 WP_043861626.1 Hsp33 family molecular chaperone HslO -
N0B28_RS01090 (N0B28_01090) 239204..240745 + 1542 WP_043861627.1 phosphoenolpyruvate carboxykinase -
N0B28_RS01095 (N0B28_01095) 240809..241096 - 288 WP_054915914.1 helix-turn-helix domain-containing protein Antitoxin
N0B28_RS01100 (N0B28_01100) 241096..241410 - 315 WP_275729910.1 hypothetical protein Toxin
N0B28_RS01105 (N0B28_01105) 241590..242018 + 429 WP_043861629.1 thioesterase family protein -
N0B28_RS01110 (N0B28_01110) 242031..242687 - 657 WP_043861630.1 response regulator transcription factor -
N0B28_RS01115 (N0B28_01115) 242727..243794 - 1068 WP_213606707.1 chemotaxis response regulator protein-glutamate methylesterase -
N0B28_RS01120 (N0B28_01120) 243791..244603 - 813 WP_043861632.1 protein-glutamate O-methyltransferase CheR -
N0B28_RS01125 (N0B28_01125) 244604..245116 - 513 WP_043861633.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11735.47 Da        Isoelectric Point: 9.8352

>T257083 WP_275729910.1 NZ_CP104044:c241410-241096 [Pseudomonas sp. SD17-1]
MLFIETSVFTSDVSSHLDDHEYLSLQVYLAEHPEAGDPIEDTGGLRKIRWAAKGKGKSGGVRVIYYYAVSASQIRLLLIY
RKGIHDTLTKKQKAVLRSLNQGWK

Download         Length: 315 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10768.29 Da        Isoelectric Point: 7.1696

>AT257083 WP_054915914.1 NZ_CP104044:c241096-240809 [Pseudomonas sp. SD17-1]
MDRNLFGRLVDSMTEMAEIDRGERKPSREFKVDAMQVRAIREATGLTQERFAQCIDVPLGTLRNWEQGRRAPEGPARALL
RAIHNDPEHVLAALA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References