Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 60624..61149 Replicon plasmid pWSM4643_3
Accession NZ_CP104043
Organism Rhizobium leguminosarum bv. viciae strain WSM4643

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N1937_RS29745 Protein ID WP_170277613.1
Coordinates 60877..61149 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N1937_RS29740 Protein ID WP_162115192.1
Coordinates 60624..60875 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N1937_RS29730 (N1937_29730) 57151..58494 - 1344 WP_026154574.1 adenylate/guanylate cyclase domain-containing protein -
N1937_RS29735 (N1937_29735) 59153..60490 + 1338 WP_260060366.1 nucleotide sugar dehydrogenase -
N1937_RS29740 (N1937_29740) 60624..60875 + 252 WP_162115192.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N1937_RS29745 (N1937_29745) 60877..61149 + 273 WP_170277613.1 Txe/YoeB family addiction module toxin Toxin
N1937_RS29750 (N1937_29750) 61204..62379 - 1176 WP_260060367.1 DUF3095 domain-containing protein -
N1937_RS29755 (N1937_29755) 62604..63083 + 480 WP_260060368.1 class I SAM-dependent methyltransferase -
N1937_RS29760 (N1937_29760) 63211..65001 - 1791 WP_222386856.1 ABC transporter ATP-binding protein -
N1937_RS29765 (N1937_29765) 65423..65878 - 456 WP_260060369.1 Rrf2 family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..407296 407296


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10792.50 Da        Isoelectric Point: 9.7234

>T257082 WP_170277613.1 NZ_CP104043:60877-61149 [Rhizobium leguminosarum bv. viciae]
MKLLWTPNSWKEYEYWQKSDQKMVEKINELLKDTKRSAFKVLGKPEPLKGDLSGFWSRRILGEHRLVYCVTGKGSDQQLE
IIQCRFHYEK

Download         Length: 273 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9243.46 Da        Isoelectric Point: 5.0066

>AT257082 WP_162115192.1 NZ_CP104043:60624-60875 [Rhizobium leguminosarum bv. viciae]
MAHVRLTEFRQNIAAYFDQVISSRAPLLVTRQGSEAMVLVAEGEYESMQETLHLLSTPANSARLRESIGQLRNGQVLESD
PTL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References