Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 61493..62018 Replicon plasmid pSRDI969_3
Accession NZ_CP104038
Organism Rhizobium leguminosarum bv. viciae strain SRDI969

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N2A41_RS29925 Protein ID WP_017968210.1
Coordinates 61746..62018 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N2A41_RS29920 Protein ID WP_260111936.1
Coordinates 61493..61744 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2A41_RS29910 (N2A41_29910) 58170..59513 - 1344 WP_260111934.1 adenylate/guanylate cyclase domain-containing protein -
N2A41_RS29915 (N2A41_29915) 60022..61359 + 1338 WP_260111935.1 nucleotide sugar dehydrogenase -
N2A41_RS29920 (N2A41_29920) 61493..61744 + 252 WP_260111936.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N2A41_RS29925 (N2A41_29925) 61746..62018 + 273 WP_017968210.1 Txe/YoeB family addiction module toxin Toxin
N2A41_RS29930 (N2A41_29930) 62073..63248 - 1176 WP_260111937.1 DUF3095 domain-containing protein -
N2A41_RS29935 (N2A41_29935) 63473..63952 + 480 WP_260111938.1 class I SAM-dependent methyltransferase -
N2A41_RS29940 (N2A41_29940) 64081..65871 - 1791 WP_260111939.1 ABC transporter ATP-binding protein -
N2A41_RS29945 (N2A41_29945) 66293..66748 - 456 WP_260111940.1 Rrf2 family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..427026 427026


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10877.52 Da        Isoelectric Point: 8.4756

>T257075 WP_017968210.1 NZ_CP104038:61746-62018 [Rhizobium leguminosarum bv. viciae]
MKLLWTPNSWEEYEYWQKSDQKMVEKINELLKDTKRSPFKVLDKPEPLKGDLSGFWSRRILGEHRLVYCVTGKGSDQQLE
IIQCRFHYEK

Download         Length: 273 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9303.61 Da        Isoelectric Point: 5.6513

>AT257075 WP_260111936.1 NZ_CP104038:61493-61744 [Rhizobium leguminosarum bv. viciae]
MAHVRLTEFRQNIATYFDQVLSSRAPLLVTRQGSEAMVLVAEGEYESMQEMLHLLSTPANSARLRESIGQLRKGQVVESD
PTL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References